2973-77-5

Basic information

• Product Name: 3,5-Dibromo-4-hydroxybenzaldehyde
• Synonyms: TIMTEC-BB SBB006529;AKOS BC-3031;AKOS B028935;3,5-DIBROMO-4-HYDROXYBENZALDEHYDE;Di-bromo-aldehyde;3,5-DIBROM-4-HYDROXYBENZALDEHYD 98%;Dibromo-4-hydroxybenzaldehyde;DIBROMO-4-HYROXYBENZALDEHYDE
• CAS NO: 2973-77-5
• Molecular Formula: C₇H₄Br₂O₂
• Molecular Weight: 279.91
• EINECS: 221-017-1
• Product Categories: Aromatic Aldehydes & Derivatives (substituted);Aldehydes;C7;Carbonyl Compounds
• Mol File: 2973-77-5.mol
• Article Data: 36

Chemical Properties

• Melting Point: 181-185 °C(lit.)
• Boiling Point: 273.3 °C at 760 mmHg
• Flash Point: 119.1 °C
• Appearance: Pink to pale brown/Crystalline Powder or Needles
• Density: 1.9661 (rough estimate)
• Vapor Pressure: 0.00345mmHg at 25°C
• Refractive Index: 1.4970 (estimate)
• Storage Temp.: Inert atmosphere,Room Temperature
• PKA: 4.72±0.23(Predicted)
• Sensitive: Air Sensitive
• BRN: 1948512
• CAS DataBase Reference: 3,5-Dibromo-4-hydroxybenzaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-Dibromo-4-hydroxybenzaldehyde(2973-77-5)
• EPA Substance Registry System: 3,5-Dibromo-4-hydroxybenzaldehyde(2973-77-5)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 2973-77-5(Hazardous Substances Data)

Usage

Description

3,5-Dibromo-4-hydroxybenzaldehyde is a marine antibiotic that is derived from marine bacteria. It is characterized by its pink to pale brown crystalline powder or needle-like appearance.

Uses

Used in Pharmaceutical Industry:
3,5-Dibromo-4-hydroxybenzaldehyde is used as an active pharmaceutical ingredient for its antibiotic properties. It is sourced from marine bacteria, which makes it a unique and potentially effective compound in the development of new drugs to combat various bacterial infections.
Used in Chemical Research:
As a crystalline compound with distinct chemical properties, 3,5-Dibromo-4-hydroxybenzaldehyde is used as a research compound in the field of chemistry. It can be utilized in the synthesis of other complex organic molecules and may contribute to the advancement of chemical knowledge and the development of novel chemical applications.
Used in Environmental Applications:
Given its origin from marine bacteria, 3,5-Dibromo-4-hydroxybenzaldehyde may also have potential applications in environmental science. It could be studied for its role in marine ecosystems or be used in the development of environmentally friendly products, such as biodegradable materials or bioactive compounds for water treatment.

InChI:InChI=1/C7H4Br2O2/c8-5-1-4(3-10)2-6(9)7(5)11/h1-3,11H

Upstream product

• 123-08-0 4-hydroxy-benzaldehyde 
• 63394-09-2 2,6-dibromo-4-(dibromomethyl)phenol 
• 532-80-9 synephrine 
• 623-11-0 1-methyl-4-nitrosobenzene 
• 7726-95-6 bromine 
• 2973-78-6 3-bromo-4-hydroxybenzylaldehyde 
• 1567388-65-1 2,6-dibromo-4-((2-hydroxyethoxy)methyl)phenol 
• 2432-12-4 2,6-dichloro-4-methylophenol 
• 107-21-1 ethylene glycol 
• 108-95-2 phenol 
• 106-44-5 p-cresol 
• 2316-62-3 3,5-dibromo-4-hydroxybenzyl alcohol 
• 104266-79-7 (3,5-Dibromo-4-hydroxy-phenyl)-hydroxy-acetonitrile 
• 344354-86-5 2,6-dibromo-4-bromomethylene-cyclohexa-2,5-dienone 

Downstream Products

• 13990-07-3 (3,5-dibromo-4-hydroxy-phenyl)-pyruvic acid 
• 5325-39-3 (E)-3-(3,5-dibromo-4-hydroxyphenyl)-2-phenylacrylic acid 
• 104700-69-8 3,5-dibromo-4-hydroxy-benzaldehyde-semicarbazone 
• 32644-57-8 4-amino-2-(3,5-dibromo-4-hydroxy-phenyl)-chromeno[4,3-d]pyrimidin-5-one 
• 119405-33-3 3,5-dibromo-4-hydroxy cinnamic acid 
• 108940-96-1 3,5-dibromo-4-methoxybenzaldehyde 
• 25315-18-8 2-(3,5-dibromo-4-hydroxybenzylidene)-1H-indene-1,3(2H)-dione 
• 3333-25-3 2,6-dibromohydroquinone 
• 859953-16-5 2,6-dibromo-4-piperidinomethyl-phenol 

Relevant articles and documents

Efficient and convenient synthesis of 3,4,5-trimethoxybenzaldehyde from p-cresol

With p-cresol as starting material, 3,4,5-trimethoxybenzaldehyde was synthesized in an overall yield of 67.4% via bromination, hydrolysis, methoxylation and methylation.

Graphene Oxide Promoted Oxidative Bromination of Anilines and Phenols in Water

The mildly acidic and oxidative nature of graphene oxide, with its large surface area available for catalytic activity, has been explored in aromatic nuclear bromination chemistry for the first time. The versatile catalytic activity of graphene oxide (GO) has been used to selectively and rapidly brominate anilines and phenols in water. The best results were obtained at ambient temperatures using molecular bromine in a protocol promoted by oxidative bromination catalyzed by GO; these transformations proceeded with 100% atom economy with respect to bromine and high selectivities for the tribromoanilines and -phenols. Reduced graphene oxide (r-GO) was observed to form after the second recycle (third use) of GO. This technique is also effective with N-bromosuccinimide (NBS) as the brominating reagent. In the case of NBS, reactions were instantaneous and the GO displayed excellent recyclability without any loss of activity over several cycles.

Magnetic nano-structured cobalt-cobalt oxide/nitrogen-doped carbon material as an efficient catalyst for aerobic oxidation of p-cresols

Efficient aerobic oxidation has been developed for the selective preparation of a sequence of valuable p-hydroxybenzaldehydes from corresponding p-cresols, using a new magnetically separable catalyst of nano-structured cobalt-cobalt oxide/nitrogen-doped carbon (CoOx@CN) material. CoOx@CN showed high activity for the 2-methoxy-4-cresol oxidation to vanillin, giving great yield (90%) and with good turnover number (210), as well as other p-cresols in good to great yields. The catalytic performance was investigated and related to the structural, chemical and magnetic properties which determined by scanning electron microscopy (SEM), transmission electron microscopy (TEM), X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), Fourier-transform infrared spectroscopy (FT-IR) and vibrating sample magnetometer (VSM). The effects of base to substrate molar ratio, catalyst concentration, temperature, and solvent on the conversion and selectivity patterns also have been studied. The investigation revealed that remarkable catalytic properties of CoOx@CN could be ascribed to the active species cobalt oxide, doped nitrogen and porous carbon with large surface area. The size of the catalyst is a key factor for catalyst performance. The ferromagnetic property of catalyst enables to recycle easily by an external magnetic field and reuse six successive times without significant activity loss.