35998-80-2Relevant articles and documents
Metal-free approach for the ?-proline mediated synthesis of nitrones from nitrosobenzene
Choi, Minho,Viji, Mayavan,Kim, Donghwan,Lee, Young Hee,Sim, Jaeuk,Kwak, Young-Shin,Lee, Kiho,Lee, Heesoon,Jung, Jae-Kyung
, p. 4182 - 4187 (2018)
An efficient, and metal-free approach for the ?-proline mediated synthesis of nitrones from nitrosobenzene and benzaldehydes has been established. The reaction undergoes very efficiently at room temperature in methanol as a solvent. The reaction is assumed to involve that the initial formation of azomethine ylide and [2 + 3] cycloaddition of nitrosobenzene, followed by the subsequent retro [2 + 3] cycloaddition could offer the desired nitrone.