471937-86-7

Basic information

• Product Name: [1-(4-AMINOPHENYL)PIPERIDIN-4-YL]METHANOL
• Synonyms: [1-(4-AMINOPHENYL)PIPERIDIN-4-YL]METHANOL;1-(4-AMINOPHENYL)-4-PIPERIDINEMETHANOL
• CAS NO: 471937-86-7
• Molecular Formula: C₁₂H₁₈N₂O
• Molecular Weight: 206.287
• Mol File: 471937-86-7.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: [1-(4-AMINOPHENYL)PIPERIDIN-4-YL]METHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: [1-(4-AMINOPHENYL)PIPERIDIN-4-YL]METHANOL(471937-86-7)
• EPA Substance Registry System: [1-(4-AMINOPHENYL)PIPERIDIN-4-YL]METHANOL(471937-86-7)

Safety Data

• Hazardous Substances Data: 471937-86-7(Hazardous Substances Data)

Usage

Description

[1-(4-aminophenyl)piperidin-4-yl]methanol, also known as 4-Amino-1-(4-aminophenyl)piperidin-4-yl)methanol, is a chemical compound with a molecular formula C13H20N2O. It is a piperidinyl derivative that contains an amino group and a phenyl group. [1-(4-aminophenyl)piperidin-4-yl]methanol has been studied for its potential use in the treatment of neurological disorders and as an inhibitor of certain enzymes. Its precise pharmacological and toxicological properties are not fully understood, and further research is needed to accurately assess its potential applications and associated risks.

Uses

Used in Pharmaceutical Industry:
[1-(4-aminophenyl)piperidin-4-yl]methanol is used as a potential therapeutic agent for neurological disorders due to its chemical structure and the possibility of interacting with specific enzymes or receptors in the nervous system.
Used in Enzyme Inhibition:
[1-(4-aminophenyl)piperidin-4-yl]methanol is used as an enzyme inhibitor, targeting specific enzymes that may be involved in the progression of certain diseases or conditions. Its effectiveness and selectivity as an inhibitor would need to be further investigated in research settings.

Upstream product

• 471938-27-9 methyl 1-(4-aminophenyl)piperidine-4-carboxylate 
• 7595-60-0 methyl 1-(4-nitrophenyl)piperidine-4-carboxylate 
• 350-46-9 4-Fluoronitrobenzene 
• 2971-79-1 isonipecotic acid methyl ester 
• 471937-85-6 [1-(4-Nitrophenyl)piperidin-4-yl]-methanol 

Downstream Products

• 1430472-08-4 (1-(4-iodophenyl)piperidin-4-yl)methanol 
• 1127735-52-7 N-(4-(2-(4-(4-(hydroxymethyl)piperidin-1-yl)phenyl)aminopyrimidin-4-yl)phenyl)methanesulfonamide 
• 1232397-87-3 (1-{4-[7-(4-methanesulfonyl-phenyl)-pyrrolo[2,1-f][1,2,4]triazin-2-ylamino]-phenyl}-piperidin-4-yl)-methanol 

Relevant articles and documents

DEGRADATION OF BRUTON'S TYROSINE KINASE (BTK) BY CONJUGATION OF BTK INHIBITORS WITH E3 LIGASE LIGAND AND METHODS OF USE

Bifunctional compounds formed by conjugating BTK inhibitor moieties with E3 ligase ligand moieties, which function to recruit targeted proteins to E3 ubiquitin ligase for degradation, and methods of preparation and uses thereof.

PYRROLOTRIAZINES AS ALK AND JAK2 INHIBITORS

The present invention provides a compound of formula (I) or a salt form thereof, wherein Q1, Q2, Q3, and Q4 are as defined herein. The compound of formula (I) has ALK and/or JAK2 inhibitory activity, and may be used to treat proliferative disorders.

Thiohydantoins and use thereof for treating diabetes

The invention relates to 2-thiohydantoin derivative compounds selected from compounds of general formula (I): as defined in the claims, and to their addition salts with an acid, notably pharmaceutically acceptable salts. The invention also relates to thei