60512-56-3

Basic information

• Product Name: Benzene, 1-(2,2-dibroMoethenyl)-4-Methyl-
• Synonyms: Benzene, 1-(2,2-dibroMoethenyl)-4-Methyl-;1-(2,2-dibroMovinyl)-4-Methylbenzene;1-(2,2-Dibromoethenyl)-4-methylbenzene;1,1-Dibromo-2-(4-methylphenyl)-1-ethene
• CAS NO: 60512-56-3
• Molecular Formula: C₉H₈Br₂
• Molecular Weight: 275.96782
• Mol File: 60512-56-3.mol
• Article Data: 51

Chemical Properties

• Melting Point: 24℃ (hexane )
• Appearance: /
• Refractive Index: 1.6272 (20℃)
• CAS DataBase Reference: Benzene, 1-(2,2-dibroMoethenyl)-4-Methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-(2,2-dibroMoethenyl)-4-Methyl-(60512-56-3)
• EPA Substance Registry System: Benzene, 1-(2,2-dibroMoethenyl)-4-Methyl-(60512-56-3)

Safety Data

• Hazardous Substances Data: 60512-56-3(Hazardous Substances Data)

Usage

General Description

Benzene, 1-(2,2-dibromoethenyl)-4-methyl- is a chemical compound with the molecular formula C10H9Br2. It is commonly used as a pesticide and fungicide in agriculture. The compound is a clear to brown liquid with a faint, sweet odor. It is slightly soluble in water and highly flammable. Exposure to this compound can cause irritation to the skin, eyes, and respiratory system. It is also known to be toxic to aquatic organisms and can have harmful effects on the environment if released into water systems. Therefore, it is important to handle and dispose of this chemical with proper caution and care.

Upstream product

• 72591-22-1 p-(2,2,2-Tribromaethyl)-toluol 
• 558-13-4 carbon tetrabromide 
• 104-87-0 4-methyl-benzaldehyde 
• 603-35-0 triphenylphosphine 
• 52693-87-5 4-methylbenzaldehyde hydrazone 
• 104-81-4 4-Methylbenzyl bromide 
• 75-25-2 Bromoform 

Downstream Products

• 130248-72-5 2-(4-methylphenyl)-1,1-bis(trimethylsilyl)-1-ethene 
• 60655-80-3 (E)-4-methylstyrenyl bromide 
• 2789-88-0 1,2-bis(4-methylphenyl)acetylene 
• 1429762-68-4 (4-methylstyryl)diphenylphosphine oxide 
• 23901-75-9 (E)-1-(diphenylphosphinyl)-2-(4-methylphenyl)ethene 
• 3287-02-3 4-(phenylethynyl)toluene 
• 24785-38-4 1-methoxy-4-[2-(4-methylphenyl)ethynyl]benzene 
• 15795-00-3 1-(4-nitrophenyl)-2-(4-tolyl)acetylene 
• 832-71-3 3-methylphenathrene 
• 2498-76-2 2-methylbenz[a]anthracene 
• 125951-09-9 (E)-1-methyl-4-[2-(phenylsulfanyl)ethenyl]benzene 
• 33429-09-3 (benzothiazol-2-yl)(p-tolyl)methanone 
• 52188-06-4 ethyl 3-(4-methylphenyl)prop-2-ynoate 
• 34793-64-1 1,5-di-(p-methylphenyl)-1,4-pentadiyn-3-one 

Relevant articles and documents

Expedient Synthesis of Bridged Bicyclic Nitrogen Scaffolds via Orthogonal Tandem Catalysis

Bridged nitrogen bicyclic skeletons have been accessed via unprecedented site- and diastereoselective orthogonal tandem catalysis from readily accessible reactants in a step economic manner. Directed Pd-catalyzed γ-C(sp3)-H olefination of aminocyclohexane with gem-dibromoalkenes, followed by a consecutive intramolecular Cu-catalyzed amidation of the 1-bromo-1-alkenylated product delivers the interesting normorphan skeleton. The tandem protocol can be applied on substituted aminocyclohexanes and aminoheterocycles, easily providing access to the corresponding substituted, aza- and oxa-analogues. The Cu catalyst of the Ullmann-Goldberg reaction additionally avoids off-cycle Pd catalyst scavenging by alkenylated reaction product. The picolinamide directing group stabilizes the enamine of the 7-alkylidenenormorphan, allowing further product post functionalizations. Without Cu catalyst, regio- and diastereoselective Pd-catalyzed γ-C(sp3)-H olefination is achieved.

Synthesis of Chiral Propargylamines, Chiral 1,2-Dihydronaphtho[2,1-b]furans and Naphtho[2,1-b]furans with C-Alkynyl N,N′-di-(tert-butoxycarbonyl)-aminals and β-Naphthols

Chiral phosphoric acid-catalyzed couplings of C-alkynyl N,N′-di-(tert-butoxycarbonyl)-aminals with β-naphthols led to chiral propargylamines in moderate to high yields with high to excellent enantioselectivity, in which the reactions underwent sequential chiral phosphoric acid-catalyzed in situ formation of N-(tert-butoxycarbonyl)-imines (N-Boc-imines) from the aminals, and 1,2-addition of β-naphthols to the N-Boc-imines. Chiral 1,2-dihydronaphtho[2,1-b]furans and naphtho[2,1-b]furans were prepared with satisfactory results when 10 mol% AgOAc and 20 mol% 2,6-lutidine or 1.2 equiv. of 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU) were added to the resulting chiral propargylamines solution, respectively.

N -tert-butyl -2 -phenylindole derivative Preparation method and application

The invention belongs to the technical field of organic synthesis, and particularly relates to N - tert-butyl -2 -phenyl indole derivatives as well as a preparation method and application thereof. The preparation method comprises the following steps: (Z)-1 - bromo -1 - phenyl -2 - styrene derivative, N, N - di-tert-butyl diazepinone, palladium catalyst, monophosphine ligand, hydrocarbon activator, base and first solvent, and N -tert-butyl -2 -aryl indole derivatives which can synthesize substituent type diversity, and the prepared N -tert-butyl -2 -aryl indole derivative can be used for preparing biologically active molecules N -2 .