6285-64-9 Usage
Description
2-FORMAMIDINO-2-PHENYLDIAZOACETAMIDE HYDROCHLORIDE, also known as 3-Amino-3-imino-2-(2-phenyldiazenyl)propanamide Hydrochloride, is a chemical compound that serves as an impurity in Temozolomide (T017775). Temozolomide is an imidazotetrazine alkylating agent with antineoplastic properties, which means it has the ability to inhibit or prevent the growth of tumors.
Uses
Used in Pharmaceutical Industry:
2-FORMAMIDINO-2-PHENYLDIAZOACETAMIDE HYDROCHLORIDE is used as an impurity in the production of Temozolomide, an antineoplastic agent. It plays a role in the development and formulation of this medication, which is utilized for the treatment of various types of cancer.
As an impurity in Temozolomide, 2-FORMAMIDINO-2-PHENYLDIAZOACETAMIDE HYDROCHLORIDE is important for quality control and assurance in the pharmaceutical industry. It helps ensure that the final product meets the required safety and efficacy standards for cancer treatment.
Check Digit Verification of cas no
The CAS Registry Mumber 6285-64-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,2,8 and 5 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 6285-64:
(6*6)+(5*2)+(4*8)+(3*5)+(2*6)+(1*4)=109
109 % 10 = 9
So 6285-64-9 is a valid CAS Registry Number.
InChI:InChI=1/C9H11N5O/c10-8(11)7(9(12)15)14-13-6-4-2-1-3-5-6/h1-5,7H,(H3,10,11)(H2,12,15)/b14-13+
6285-64-9Relevant articles and documents
Xanthine oxidase (XO): Relative configuration of complexes formed by the enzyme, 2- or 8-N-alkylhypoxanthines and 2-N-alkyl-8-azahypoxanthines. XII
Biagi,Giorgi,Livi,Scartoni,Tonetti,Lucacchini
, p. 357 - 374 (2007/10/02)
Several 2- or 8-n-alkyl-hypoxanthines and a 2,8-di-n-pentylhypoxanthine were synthesized and tested as substrates or inhibitors of Xanthine Oxidase (XO). 8-Alkyl derivatives showed a substrate behaviour, whereas 2-alkyl substituted compounds were non-substrates and inhibitors. 2,8-di-n-pentylhypoxanthine was ineffective as inhibitor. The comparison between their activity allowed us to conclude that the complexes formed by the enzyme and the cited n-alkylhypoxanthines or 2-n -alkyl-8-azahypoxanthines involve their N(3) and N(9) positions in all the cases. The position of the n-alkyl chain determines the disposition of the molecule inside the complex: 2-n-alkyl-hypoxanthines and 2-n-alkyl-8-azahypoxanthines gave complexes with the same orientation of heterocyclic moieties, opposite that given by 8-n-alkyl-hypoxanthines.
