72-17-3 Usage
Description
Sodium lactate, also known as the sodium salt of lactic acid, is an organic compound with a mild saline taste. It is a hygroscopic agent and a component of the natural moisturizing factor (NMF). Sodium lactate is produced by fermenting a sugar source, such as corn or beets, and then neutralizing the resulting lactic acid to create a compound with the formula NaC3H5O3. It is a colorless, slightly syrupy liquid that is odorless or has a slight odor and is known for its antimicrobial and antioxidant effects.
Uses
Used in Food Industry:
Sodium lactate is used as a preservative, acidity regulator, and bulking agent. It has the E number E325 and is available in both liquid and powder forms. It is a safe organic preservative for various food products, such as fish and sausage.
Used in Cosmetics Industry:
Sodium lactate is used as an effective humectant and moisturizer in cosmetics, including aftershave lotions and other similar products like liquid soaps.
Used in Textile Industry:
Sodium lactate is used as a substitute for glycerol in calico printing and as a plasticizer for casein.
Used in Automotive Industry:
Sodium lactate is used as a corrosion inhibitor in alcohol antifreeze mixtures.
Used in Pharmaceutical Industry:
Sodium lactate is used to treat arrhythmias caused by overdosing of class I antiarrhythmics and pressor sympathomimetics, which can cause hypertension. It can also be given intravenously as a source of bicarbonate for preventing or controlling mild to moderate metabolic acidosis in patients with restricted oral intake whose oxidative processes are not seriously impaired. However, its use in lactic acidosis is contraindicated.
Used in Medical Treatment:
Sodium lactate is advocated in the treatment of bradycardia and asystole associated with complete heart block.
References
[1] M. Suan Brewer, F. Mckeith, S. E. Martin, A. W. Dallmier and J. Meyer, Sodium Lactate Effects on Shelf-Life, Sensory, and Physical Characteristics of Fresh Pork Sausage, Journal of Food Science, 1991, vol. 56, 1176-1178
[2] Khalid Ibrahim Sallam, Antimicrobial and antioxidant effects of sodium acetate, sodium lactate, and sodium citrate in refrigerated sliced salmon, Food Control, 2007, vol. 18, 566-575
[3] Dawn C. Minetti, Clear, hydroalcoholic aftershave lotion which moisturizes, conditions, and prevents irritation, Patent US 4758599 A, 1986
[4] John F. Murray and S. H. Boyer, Ventricular Arrhythmias after Intravenous Sodium Lactate in Heart Block, Circulation, 1957, vol. 15, 547-558
Pharmaceutical Applications
Sodium lactate is widely used in cosmetics, food products and
pharmaceutical applications including parenteral and topical
formulations.
Therapeutically, sodium lactate is used in infusions as a
component of Ringer-lactate solution; as an alternative for sodium
hydrogencarbonate in light acidosis; as a rehydrating agent; and as
a carrier for electrolyte concentrates or medicines in perfusion/
infusion solutions.
Biochem/physiol Actions
Sodium lactate functions as a buffer to maintain osmotic and charge balance. It serves as a humectant, especially in cosmetic preparations. It acts a flavoring agent in meat and poultry products. Sodium lactate also plays a role as a buffer. Sodium lactate could be an alternative source of energy and an oxidative substrate in case of lack of oxygen in brain cells.
Food additive
Sodium lactate need not be restricted by someone avoiding milk or those with a milk allergy.In general, lactates such as sodium, calcium, and potassium lactate are salts derived from the neutralization of lactic acid and most commercially used lactic acids are fermented from dairy - free products such as cornstarch, potatoes, or molasses. Sugar or tapioca additionally may be used. However some lactic acid is fermented from dairy products such as whey and lactose . Whey is made of up 6.5 % solids of which 4.8% is solid lactose . Waste whey typically is used to produce lactic acid when the whey itself is produced as waste during the manufacture of certain dairy products . As a result, such dairy-type lactic acid generally goes back into dairy products, such as ice cream and cream cheese, rather than into non - dairy products. Moreover, although the lacticacid starter culture to ferment corn or beets may contain milk, sodium lactate does not contain milk protein and need not be restricted by someone avoiding milk or those with a milk allergy.
Safety
Sodium lactate occurs naturally in the body and is involved in
physiological processes. It is generally regarded as a relatively
nontoxic and nonirritant material when used as an excipient. Low
concentrations are well tolerated by skin and eye mucosa, although
higher concentrations should be avoided.
LD50 (rat, IP): 2 g/kg
storage
Sodium lactate should be stored in a well-closed container in a cool,
dry, place. Sodium lactate is combustible and decomposes upon
heating.
Regulatory Status
GRAS listed (not for infant formulas). Included in the FDA Inactive
Ingredient Database (epidural, IM, IV, and SC injections; oral
suspensions; topical gels and solutions). Included in nonparenteral medicines licensed in the UK. Included in the Canadian List of
Acceptable Non-medicinal Ingredients.
Check Digit Verification of cas no
The CAS Registry Mumber 72-17-3 includes 5 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 2 digits, 7 and 2 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 72-17:
(4*7)+(3*2)+(2*1)+(1*7)=43
43 % 10 = 3
So 72-17-3 is a valid CAS Registry Number.
InChI:InChI=1/C3H6O3.Na/c1-2(4)3(5)6;/h2,4H,1H3,(H,5,6);/q;+1
