76-37-9 Usage
Description
Tetrafluoro-1-propanol, also known as 2,2,3,3-Tetrafluoro-1-propanol, is a fluorinated fine chemical with unique properties. It is a colorless liquid with a low boiling point and high solubility in water. Its molecular structure consists of a hydroxyl group attached to a propanol backbone with four fluorine atoms, which imparts it with special characteristics such as high chemical stability, low surface tension, and excellent solubility in various solvents.
Uses
Used in Optical Data Storage Industry:
Tetrafluoro-1-propanol is used as a dye solvent in the CD-R(W) and DVD-R(W) industry. Its unique properties, such as low surface tension and high solubility, make it an ideal choice for this application, ensuring the proper functioning and performance of optical data storage devices.
Used in Textile Treatment Industry:
Tetrafluoro-1-propanol is used as a textile treatment agent. Its properties, such as high chemical stability and low surface tension, enable it to provide various benefits to textiles, including improved water and oil repellency, stain resistance, and easy cleaning.
Used in Pharmaceutical Industry:
Tetrafluoro-1-propanol is used in the production of pharmaceuticals. Its unique properties, such as high solubility in water and various solvents, make it a valuable ingredient in the formulation of drugs, particularly those requiring solubility enhancement or specific chemical stability.
Used as a Replacement for Freon 22 Detergent:
Tetrafluoro-1-propanol is an ideal replacement for Freon 22 detergent due to its environmentally friendly nature and similar properties. It can be used in various applications where Freon 22 was previously used, such as in cleaning agents and degreasers, without causing harm to the environment or contributing to the depletion of the ozone layer.
Purification Methods
Tetrafluoro-1-propanol (450mL) is added to a solution of 2.25g of NaHSO3 in 90mL of water, shaken vigorously and set aside for 24hours. The fraction distilling at or above 99o is refluxed for 4hours with 5-6g of KOH and rapidly distilled, followed by a final fractional distillation. [Kosower & Wu J Am Chem Soc 83 3142 1961.] Alternatively, shake the alcohol with alumina for 24hours, dry it overnight with anhydrous K2CO3 and distil it, taking the middle fraction (b 107-108o). [Beilstein 1 IV 2438.]
Check Digit Verification of cas no
The CAS Registry Mumber 76-37-9 includes 5 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 2 digits, 7 and 6 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 76-37:
(4*7)+(3*6)+(2*3)+(1*7)=59
59 % 10 = 9
So 76-37-9 is a valid CAS Registry Number.
InChI:InChI=1S/C3H4F4O/c4-2(5)3(6,7)1-8/h2,8H,1H2
76-37-9Relevant articles and documents
Thermal desulfurization of (Alkoxymethyl)thiiranes
Nalet'Ko,Pervova,Gorbunova,Zapevalov, A. Ya,Toporova,Saloutin
, p. 2120 - 2124 (2015/02/02)
Reaction of (alkoxymethyl)oxiranes with thiourea in methanol has afforded the corresponding thiiranes, and catalyst-free thermal desulfurization of the products has been studied. The major products of desulfurization are alcohols and alkenes, both in the cases of (polyfluoroalkyloxymethyl)thiiranes and their non-fluorinated analogs. Longer alkyl chain in thiiranes favors formation of alcohols over alkenes formation in the course of desulfurization.
Polyfluoroalkoxy phosphonic and phosphinic acid derivatives: II. Reversible esterase inhibitors
Krutikova,Krutikov,Erkin
experimental part, p. 434 - 439 (2010/08/04)
Polyfluoroalkyl esters of phosphoric, alkylphosphonic and 1-hydroxypolyfluoroalkylphosphonic acids exhibited significant antiesterase activity against various esterases of animal and microbial origin. Moreover, with some compounds reversible inhibition of enzymes was observed due to the specific influence of hydrophobic fragments of the target products.
Transformation of perfluorinated benzocycloalkenes and alkylbenzenes to their carbonyl derivatives under the action of CF3COOH/SbF5
Zonov, Yaroslav V.,Karpov, Victor M.,Platonov, Vyacheslav E.
, p. 1058 - 1064 (2008/02/10)
Perfluorinated benzocycloalkenes (benzocyclobutene, indan, tetralin), alkylbenzocycloalkenes and alkylbenzenes react with CF3COOH/SbF5 at 20-50 °C giving the corresponding carbonyl derivatives.