79-33-4 Usage
Description
L(+)-Lactic acid, also known as L-lactic acid or (+)-lactic acid, is an organic compound that occurs naturally in small quantities in the blood and muscle fluid of humans and animals. It is a chiral molecule with a hydroxyl group and a carboxyl group attached to the same carbon atom. The lactic acid concentration increases in muscle and blood after vigorous activity. L(+)-Lactic acid is also present in various organs, such as the liver, kidney, thymus gland, human amniotic fluid, and others.
Uses
Used in Medical Applications:
L(+)-Lactic acid is used for fluid resuscitation after blood loss due to trauma, surgery, or burn injury. It helps restore the balance of electrolytes and maintain proper hydration in the body.
Used in Agricultural Industry:
L(+)-Lactic acid is used as a tanning agent in the leather processing industry, improving the quality and durability of leather products.
Used in Chemical Industry:
L(+)-Lactic acid is used as an electroplating agent, pH regulator, cleaning/washing agent, and in the production of large scale and fine chemicals.
Used in Pharmaceutical Industry:
L(+)-Lactic acid is used as a component in substrate solution II for lactate dehydrogenase reaction, an additive in storage solution A, and as a supplement in the artificial gastric juice preparation for evaluating the degree of resistance of Lactobacillus to gastric stresses.
Used in Cosmetics Industry:
L(+)-Lactic acid is used as a pH regulator in fabric finishing and in the production of soaps, paints, coatings, and cleaning products.
Used in Food and Feed Industry:
L(+)-Lactic acid is used as a food/feed additive and to flavor animal feeds, enhancing the taste and nutritional value of these products.
Used in Other Industries:
L(+)-Lactic acid is also used in mining, health services, agriculture-forestry-fishing, and building and construction work, contributing to various processes and applications in these fields.
Flammability and Explosibility
Notclassified
Biochem/physiol Actions
L-(+)-Lactic acid is used as a substrate for lactic acid dehydrogenase and lactate oxidase.
Purification Methods
Purify lactic acid by fractional distillation at 0.1mm pressure, followed by fractional crystallisation from diethyl ether/isopropyl ether (1:1, dried with sodium). [Borsook et al. J Biol Chem 102 449 1933.] The solvent mixture, *benzene/diethyl ether (1:1) containing 5% pet ether (b 60-80o) has also been used. [Brin Biochemical Preparations 3 61 1953, Beilstein 3 IV 633.]
Check Digit Verification of cas no
The CAS Registry Mumber 79-33-4 includes 5 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 2 digits, 7 and 9 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 79-33:
(4*7)+(3*9)+(2*3)+(1*3)=64
64 % 10 = 4
So 79-33-4 is a valid CAS Registry Number.
InChI:InChI=1/C3H6O3/c1-2(4)3(5)6/h2,4H,1H3,(H,5,6)/t2-/m0/s1
79-33-4Relevant articles and documents
γ-Valerolactone-introduced controlled-isomerization of glucose for lactic acid production over an Sn-Beta catalyst
Zhao, Xinpeng,Zhou, Zhimin,Luo, Hu,Zhang, Yanfei,Liu, Wang,Miao, Gai,Zhu, Lijun,Kong, Lingzhao,Li, Shenggang,Sun, Yuhan
supporting information, p. 2634 - 2639 (2021/04/22)
Combined experiments and density functional theory (DFT) calculations provided insights into the role of environment-friendly γ-valerolactone (GVL) as a solvent in the hydrothermal conversion of glucose into lactic acid (LA) over the post-synthesized Sn-Beta catalyst. By introducing 2.0 wt% GVL, a much higher yield of LA (72.0 wt%) was obtained than that in pure water (60.1 wt%) at 200 °C, 4 MPa N2, and 30 min in a batch reactor. The GVL effectively suppressed the isomerization of glucose into fructose in a controlled-transfer mode, resulting in a lower fructose concentration. Thermogravimetry-differential analysis and DFT calculations demonstrated that the competitive adsorption between GVL and glucose happened at the open Sn sites over the Sn-Beta catalyst, which led to a controlled isomerization rate in water. Further increasing the content of GVL to 20.0 wt%, the higher yield of LA (74.0 wt%) was attributed to the more efficient competitive adsorption while also inhibiting carbon deposition.
METHODS FOR SYNTHESIZING ANHYDROUS LACTIC ACID
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Paragraph 0038; 0056, (2021/11/13)
A method of synthesizing anhydrous lactic acid is provided by reacting a compound of formula (Ia): with an acid compound of formula HnX in a first solvent to produce a reaction mixture comprising a compound of formula (Ib) and a lactic acid compound of formula (I) in solution with the first solvent and/or water. n is an integer other than 0, x is 0, or an integer other than 0, M is an alkali metal or alkaline earth metal and X is the conjugate base of the acid compound of formula HnX. The resulting reaction mixture is filtered to produce a filtrate containing lactic acid in solution. The filtrate is crystalized from a second solvent to produce anhydrous lactic acid.
Epimerization-suppressed organocatalytic synthesis of poly-L-lactide in supercritical carbon dioxide under plasticizing conditions
Mase, Nobuyuki,Moniruzzaman,Yamamoto,Sato,Narumi, Tetsuo,Yanai, Hikaru
, (2019/08/06)
Herein, an efficient (>95% yield, >99.0% ee) Br?nsted acid-catalyzed synthetic method of poly-L-lactide (PLLA) in supercritical carbon dioxide (scCO2) under plasticizing conditions is presented. High-performance liquid chromatography analysis of the PLLA hydrolysis products indicated that, as opposed to the case of organic solvents, the use of a nucleophilic catalyst in scCO2 suppressed the epimerization. The highly stereochemically pure PLLA prepared by the developed method under metal-free conditions meets the criteria of medicinal/engineering applications.