79251-83-5

Basic information

• Product Name: N-acyl-N^ε-benzoyl-L-lysine methyl ester
• Synonyms: N-acyl-N^ε-benzoyl-L-lysine methyl ester
• CAS NO: 79251-83-5
• Molecular Weight: 306.362
• Mol File: 79251-83-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: N-acyl-N^ε-benzoyl-L-lysine methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: N-acyl-N^ε-benzoyl-L-lysine methyl ester(79251-83-5)
• EPA Substance Registry System: N-acyl-N^ε-benzoyl-L-lysine methyl ester(79251-83-5)

Safety Data

• Hazardous Substances Data: 79251-83-5(Hazardous Substances Data)

Upstream product

• 19264-68-7 9-benzoyl-9H-carbazole 
• 13515-95-2 L-lysine methyl ester hydrochloride 
• 108-24-7 acetic anhydride 
• 61571-00-4 Nε-benzoyl-L-lysine methyl ester 
• 1946-82-3 N-Ac-L-Lys-OH 
• 98-88-4 benzoyl chloride 
• 70326-37-3 phenyl(2-thioxothiazolidin-3-yl)methanone 
• 1219-46-1 N⁶-benzoyl-L-lysine 
• 56-87-1 L-lysine 
• 79251-84-6 N^ε-benzoyl-L-lysine methyl ester hydrochloride 

Downstream Products

• 1450753-95-3 (S)-methyl-2-acetamido-6-[2-(4-nitrobenzamido)benzamido]hexanoate 

Relevant articles and documents

N-acylcarbazole as a selective transamidation reagent

N-acylation reaction offers an opportunity to develop an efficient synthesis of amide group-containing molecules. We found that N-acyl carbazoles showed remarkable selectivity in transamidation. Sterically less hindered primary amines are selectively acylated with N-acyl carbazoles without any additives. Various functional groups such as alcohol, phenol, indole, and aniline moieties are tolerated under mild conditions. The synthetic utility was displayed in one-pot synthesis of an N-acyl polyamine natural product. The terminal amines of spermidine were selectively benzoylated with N-benzoyl carbazole, followed by acetylation reaction accomplished the total synthesis in a highly efficient manner.

Peptide-bond Formation, Chemoselective Acylation of Amino Acids, and Crosslinking Reaction between Amino Acids Utilizing a Functional Five-membered Heterocycle, 1,3-Thiazolidine-2-thione

The monitored aminolysis of 3-acyl-1,3-thiazolidine-2-thiones has been extended to the peptide-bond formation, the chemoselective acylation of amino acids having multifunctional groups, and the crosslinking reaction between amino acids.