9028-56-2

Basic information

• Product Name: 3ALPHA-HYDROXYSTEROID DEHYDROGENASE
• Synonyms: 3ALPHA-HYDROXYSTEROID DEHYDROGENASE;3ALPHA-HYDROXYSTEROID: NAD[P]+ OXIDOREDUCTASE;EC 1.1.1.50;EC: 1.1.1.50;3alpha-hydroxysteroid dehydrogenase F. pseu. test. ~9 U/mg;3alpha-Hydroxysteroid Dehydrogenase from Pseudomonas testosteroni;Dehydrogenase, 3alpha-hydroxy steroid;HYDROXYSTEROID OXIDOREDUCTASE
• CAS NO: 9028-56-2
• Molecular Weight: 0
• EINECS: 232-839-5
• Product Categories: Oxidoreductases;Specialty Enzymes
• Mol File: 9028-56-2.mol
• Article Data: 0

Chemical Properties

• Appearance: /ammonium sulfate suspension
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 3ALPHA-HYDROXYSTEROID DEHYDROGENASE(CAS DataBase Reference)
• NIST Chemistry Reference: 3ALPHA-HYDROXYSTEROID DEHYDROGENASE(9028-56-2)
• EPA Substance Registry System: 3ALPHA-HYDROXYSTEROID DEHYDROGENASE(9028-56-2)

Safety Data

• Safety Statements: 24/25
• WGK Germany: 3
• Hazardous Substances Data: 9028-56-2(Hazardous Substances Data)

Usage

Description

3ALPHA-HYDROXYSTEROID DEHYDROGENASE, also known as 3α-Hydroxysteroid Dehydrogenase, is an enzyme that plays a crucial role in the metabolism of steroid hormones. It catalyzes the interconversion of 3-hydroxy steroid compounds and their corresponding ketones, which are essential for various biological processes. This enzyme is derived from Pseudomonas testosterone and is available in a powder form, making it suitable for various applications in different industries.

Uses

Used in Biotechnology Industry:
3ALPHA-HYDROXYSTEROID DEHYDROGENASE is used as a key component in the preparation of composite electrode platforms for the determination of androsterone in potassium phosphate buffer. This application is crucial for the development of biosensors and diagnostic tools in the biotechnology field.
Used in Medical Diagnostics:
In the medical diagnostics industry, 3ALPHA-HYDROXYSTEROID DEHYDROGENASE is utilized for the bioluminescent assay of bile acids in serum. This method allows for the accurate and sensitive detection of bile acids, which are essential for understanding various liver and metabolic disorders.
Used in Clinical Chemistry:
3ALPHA-HYDROXYSTEROID DEHYDROGENASE is employed in the total bile salts assay using an enzymatic method. This application is vital for assessing liver function and diagnosing conditions related to bile salt metabolism, such as cholestasis and liver disease.
Overall, 3ALPHA-HYDROXYSTEROID DEHYDROGENASE is a versatile enzyme with applications in various industries, including biotechnology, medical diagnostics, and clinical chemistry. Its ability to catalyze the conversion of steroid hormones makes it an essential tool for developing diagnostic methods and understanding the role of these hormones in various biological processes.

Biochem/physiol Actions

3α-hydroxysteroid dehydrogenase (3α-HSD) may help to modulate the occupancy of the androgen receptor (AR) in androgen target tissues. It may also act in hindering androgen action.