91591-64-9

Basic information

• Product Name: 2-Chloro-4,5,6-trimethylnicotinonitrile
• Synonyms: 2-Chloro-4,5,6-trimethylnicotinonitrile
• CAS NO: 91591-64-9
• Molecular Formula: C₉H₉ClN₂
• Molecular Weight: 180.64
• Mol File: 91591-64-9.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-Chloro-4,5,6-trimethylnicotinonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Chloro-4,5,6-trimethylnicotinonitrile(91591-64-9)
• EPA Substance Registry System: 2-Chloro-4,5,6-trimethylnicotinonitrile(91591-64-9)

Safety Data

• Hazard Codes: T
• Statements: 25
• Safety Statements: 45
• Hazardous Substances Data: 91591-64-9(Hazardous Substances Data)

Usage

Description

2-Chloro-4,5,6-trimethylnicotinonitrile is a chemical compound with the molecular formula C9H10ClN3. It is a white solid with a molecular weight of 191.65 g/mol. 2-Chloro-4,5,6-trimethylnicotinonitrile is often used in organic synthesis and medicinal chemistry as a building block for creating various compounds and drugs. It is also a key intermediate in the synthesis of pharmaceuticals and agrochemicals. Known for its ability to form stable complexes with metal ions, 2-Chloro-4,5,6-trimethylnicotinonitrile is a valuable molecule in coordination chemistry. Careful handling is required, as it can be harmful if it comes into contact with the skin or eyes, or if it is inhaled or ingested.

Uses

Used in Organic Synthesis:
2-Chloro-4,5,6-trimethylnicotinonitrile is used as a building block in organic synthesis for creating various compounds and drugs. Its unique structure and reactivity make it a versatile component in the development of new chemical entities.
Used in Medicinal Chemistry:
In medicinal chemistry, 2-Chloro-4,5,6-trimethylnicotinonitrile is used as a key intermediate in the synthesis of pharmaceuticals. Its properties allow for the creation of a wide range of therapeutic agents.
Used in Agrochemicals:
2-Chloro-4,5,6-trimethylnicotinonitrile is also utilized as an intermediate in the synthesis of agrochemicals, contributing to the development of effective products for agricultural applications.
Used in Coordination Chemistry:
Due to its ability to form stable complexes with metal ions, 2-Chloro-4,5,6-trimethylnicotinonitrile is used in coordination chemistry, playing a significant role in the study and application of metal-organic frameworks and other related areas.

Upstream product

• 91591-59-2 2-hydroxy-4,5,6-trimethyl-nicotinonitrile 
• 23652-87-1 4-amino-3-methyl-3-penten-2-one 
• 128917-84-0 4,5,6-trimethyl-2-thioxo-1,2-dihydropyridine-3-carbonitrile 
• 91591-59-2 4,5,6-trimethyl-2 -oxo-1,2-dihydropyridine-3-carbonitrile 
• 1113-62-8 4-amino-3-methylpent-3-en-2-one 
• 815-57-6 3-Methyl-2,4-pentanedione 

Downstream Products

• 128917-84-0 2-mercapto-4,5,6-trimethyl-nicotinonitrile 
• 18441-60-6 2,3,4,5-tetramethyl pyridine 
• 2233-29-6 2,3,4-lutidine 

Relevant articles and documents

INDAZOLES AND AZAINDAZOLES AS LRRK2 INHIBITORS

The present invention is directed to indazole and azaindazole compounds which are inhibitors of LRRK2 and are useful in the treatment of CNS disorders.

REACTIONS OF 2-CYANOTHIOACETAMIDE WITH α-ALKYLATED β-DIKETONES: SYNTHESIS OF PYRIDINE-2(1H)-THIONE, THIENOPYRIDINE AND PYRIDOPYRAZOLE DERIVATIVES

A novel synthesis of pyridine-2(1H)-thiones, thienopyridines and pyridopyrazoles utilizing 2-cyanothioacetamide and α-alkylated β-diketones as starting components is described.