95546-66-0

Basic information

• Product Name: Thieno[2,3-c]isoquinoline-2-carboxylic acid, 1-amino-6,7,8,9-tetrahydro-5-methyl-
• CAS NO: 95546-66-0
• Molecular Formula: C13H14N2O2S
• Mol File: 95546-66-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Thieno[2,3-c]isoquinoline-2-carboxylic acid, 1-amino-6,7,8,9-tetrahydro-5-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Thieno[2,3-c]isoquinoline-2-carboxylic acid, 1-amino-6,7,8,9-tetrahydro-5-methyl-(95546-66-0)
• EPA Substance Registry System: Thieno[2,3-c]isoquinoline-2-carboxylic acid, 1-amino-6,7,8,9-tetrahydro-5-methyl-(95546-66-0)

Safety Data

• Hazardous Substances Data: 95546-66-0(Hazardous Substances Data)

Upstream product

• 95547-02-7 (4-Cyano-1-methyl-5,6,7,8-tetrahydro-isoquinolin-3-ylsulfanyl)-acetic acid 
• 95546-96-6 1-methyl-3-thioxo-2,3,5,6,7,8-hexa-hydroisoquinoline-4-carbonitrile 
• 35248-30-7 2-acetyl-1-(1-piperidyl)-1-cyclohexene 
• 874-23-7 2-acetylcyclohexanone 
• 932-66-1 1-cyclohexenyl methyl ketone 

Relevant articles and documents

CYCLIZATION OF NITRILES. XIV. SYNTHESIS AND REACTIONS OF 1-ALKYL-4-CYANO-5,6,7,8-TETRAHYDRO-3(2H)-ISOQUINOLINETHIONES AND SOME OF THEIR ANALOGS

1-Alkyl-4-cyano-5,6,7,8-tetrahydro-3(2H)-isoquinolinethiones and 6-methyl-4,5-trimethylene-3-cyano-2(1H)-pyridinethione were synthesized by the reaction of cyclic enamino ketones and 1,3-diketones with nitriles containing an active methylene group.The products are readily alkylated by halogen derivatives of the sulfur atom with the formation of substituted 3-alkylthio-4-cyano-5,6,7,8-tetrahydroisoquinolines, 3-aminothienopyridines, and 3-aminothienoquinolines, which were used in the synthesis of various heterocyclic systems.The corresponding 1-alkyl-4-cyano-5,6,7,8-tetrahydro-3(2H)-isoquinolines are alkylated preferentially at the ring nitrogen atom.