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4-FLUORO-4-(1-(4-PHENYL)PIPERAZINO)-BUTYROPHENONE

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Name

4-FLUORO-4-(1-(4-PHENYL)PIPERAZINO)-BUTYROPHENONE

EINECS N/A
CAS No. 2354-61-2 Density 1.137g/cm3
PSA 23.55000 LogP 3.61370
Solubility N/A Melting Point N/A
Formula C20H23 F N2 O Boiling Point 481.2°Cat760mmHg
Molecular Weight 326.45 Flash Point 244.8°C
Transport Information N/A Appearance N/A
Safety Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion, and subcutaneous routes. When heated to decomposition it emits very toxic fumes of F and NOx. Risk Codes N/A
Molecular Structure Molecular Structure of 2354-61-2 (1-Butanone, 1-(4-fluorophenyl)-4-(4-phenyl-1-piperazinyl)-) Hazard Symbols N/A
Synonyms

Butyrophenone,4'-fluoro-4-(4-phenyl-1-piperazinyl)- (6CI,7CI,8CI); Butropipazon;Butyropipazone; NSC 170975; R 1892; g-(4-Phenylpiperazino)-4-fluorobutyrophenone

Article Data 7

4-FLUORO-4-(1-(4-PHENYL)PIPERAZINO)-BUTYROPHENONE Chemical Properties

4-FLUORO-4-(1-(4-PHENYL)PIPERAZINO)-BUTYROPHENONE (2354-61-2) has the Molecular Formula of C20H23FN2O and the Molecular Weight of 326.45.The Density is 1.137g/cm3 .
Besides,the Boiling Point and the Flash Point of 4-FLUORO-4-(1-(4-PHENYL)PIPERAZINO)-BUTYROPHENONE (2354-61-2) are 481.2°C at 760mmHg and 244.8°C .
The structure:

4-FLUORO-4-(1-(4-PHENYL)PIPERAZINO)-BUTYROPHENONE Toxicity Data With Reference

1.   

orl-rat LD50:550 mg/kg

   PHMGBN    Pharmacology: International Journal of Experimental and Clinical Pharmacology. 15 (1977),485.
2.   

scu-rat LD50:550 mg/kg

   MDCHAG    Medicinal Chemistry: A Series of Monographs. 4 (2)(1967),199.
3.   

ivn-rat LD50:32 mg/kg

   27ZQAG    Psychotropic Drugs and Related Compounds E. Usdin andD.H. Efron,2nd ed.,Washington, DC.: 1972,186.
4.   

orl-mus LD50:650 mg/kg

   PHMGBN    Pharmacology: International Journal of Experimental and Clinical Pharmacology. 15 (1977),485.
5.   

ipr-mus LD50:76 mg/kg

   27ZQAG    Psychotropic Drugs and Related Compounds E. Usdin andD.H. Efron,2nd ed.,Washington, DC.: 1972,186.
6.   

ivn-mus LD50:24 mg/kg

   27ZQAG    Psychotropic Drugs and Related Compounds E. Usdin andD.H. Efron,2nd ed.,Washington, DC.: 1972,186.
Toxicity can affect the behavioral - toxic psychosis,
Sense Organs and Special Senses (Eye) - ptosis Autonomic Nervous System - central sympatholytic Behavioral - alteration of classical conditioning.

4-FLUORO-4-(1-(4-PHENYL)PIPERAZINO)-BUTYROPHENONE Safety Profile

Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion, and subcutaneous routes. When heated to decomposition 4-FLUORO-4-(1-(4-PHENYL)PIPERAZINO)-BUTYROPHENONE (2354-61-2) emits very toxic fumes of F- and NOx.
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