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5-Methoxy-2-nitrophenol

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Name

5-Methoxy-2-nitrophenol

EINECS N/A
CAS No. 704-14-3 Density 1.367 g/cm3
PSA 75.28000 LogP 1.83220
Solubility N/A Melting Point 92-94 °C
Formula C7H7NO4 Boiling Point 297.4 °C at 760 mmHg
Molecular Weight 169.137 Flash Point 133.7 °C
Transport Information N/A Appearance yellow crystals or powder
Safety 26-36-37/39 Risk Codes 37/38-41-36/37/38
Molecular Structure Molecular Structure of 704-14-3 (5-Methoxy-2-nitrophenol) Hazard Symbols IrritantXi
Synonyms

2-Hydroxy-4-methoxynitrobenzene;2-Nitro-5-methoxyphenol;3-Methoxy-6-nitrophenol;5-Methoxy-2-nitrophenol;NSC1167;

Article Data 22

5-Methoxy-2-nitrophenol Specification

The 5-Methoxy-2-nitrophenol, with the CAS registry number 704-14-3, is also known as 2-Nitro-5-methoxyphenol. It belongs to the product categories of Classes of Aromatic Phenols; Organic Building Blocks; Oxygen Compounds; Phenols. This chemical's molecular formula is C7H7NO4 and molecular weight is 169.13. What's more, its systematic name is 5-Methoxy-2-nitrophenol.

Physical properties of 5-Methoxy-2-nitrophenol are: (1)ACD/LogP: 1.91; (2)# of Rule of 5 Violations: 0; (3)#H bond acceptors: 5; (4)#H bond donors: 1; (5)#Freely Rotating Bonds: 3; (6)Polar Surface Area: 64.28Å2; (7)Index of Refraction: 1.583; (8)Molar Refractivity: 41.35 cm3; (9)Molar Volume: 123.7 cm3; (10)Polarizability: 16.39×10-24cm3; (11)Surface Tension: 53.4 dyne/cm; (12)Density: 1.367 g/cm3; (13)Flash Point: 133.7 °C; (14)Enthalpy of Vaporization: 55.87 kJ/mol; (15)Boiling Point: 297.4 °C at 760 mmHg; (16)Vapour Pressure: 0.000764 mmHg at 25°C.

Preparation: this chemical can be prepared by 3-methoxy-phenol. This reaction will need reagent claycop and solvent acetic anhydride and diethyl ether. The yield is about 79%.
5-Methoxy-2-nitrophenol is prepared by 3-methoxy-phenol

Uses of 5-Methoxy-2-nitrophenol: it can be used to produce 2-Amino-5-methoxy-phenol at 70°C. It will need reagent aq. formic acid and KOH and solvent ethanol with the reaction time of 4 hours.This reaction will also need catalyst Pd/C. The yield is about 59%.              
5-Methoxy-2-nitrophenol  can bu used to produce 2-Amino-5-methoxy-phenol

When you are using this chemical, please be cautious about it as the following:
It may cause inflammation to the skin or other mucous membranes. It is irritating to eyes, respiratory system and skin. It has the serious damage to eyes. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. You should wear suitable protective clothing, gloves and eye/face protection.

You can still convert the following datas into molecular structure:
(1)SMILES: O=[N+]([O-])c1ccc(OC)cc1O
(2)Std. InChI: InChI=1S/C7H7NO4/c1-12-5-2-3-6(8(10)11)7(9)4-5/h2-4,9H,1H3
(3)Std. InChIKey: NRTULWPODYLFOJ-UHFFFAOYSA-N

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