Basic Information | Post buying leads | Suppliers | Cas Database |
Name |
6-Bromo-4-hydroxy-3-nitroquinoline |
EINECS | N/A |
CAS No. | 853908-50-6 | Density | 1.878 g/cm3 |
PSA | 78.94000 | LogP | 3.13430 |
Solubility | N/A | Melting Point |
N/A |
Formula | C9H5BrN2O3 | Boiling Point | 389.339 °C at 760 mmHg |
Molecular Weight | 269.054 | Flash Point | 189.266 °C |
Transport Information | N/A | Appearance | N/A |
Safety | Risk Codes | N/A | |
Molecular Structure | Hazard Symbols | N/A | |
Synonyms |
6-Bromo-3-nitroquinolin-4-ol; |
Article Data | 31 |
6-bromoquinolin-4-ol
6-bromo-3-nitroquinolin-4-ol
Conditions | Yield |
---|---|
With nitric acid; propionic acid for 2h; | 64.5% |
With nitric acid In propionic acid at 125℃; for 2h; | 50.2% |
With nitric acid In propionic acid at 125℃; for 2h; | 50% |
With nitric acid In propionic acid at 125℃; for 2h; |
(E)-5-bromo-2-((2-nitrovinyl)amino)benzoic acid
6-bromo-3-nitroquinolin-4-ol
Conditions | Yield |
---|---|
With potassium acetate In acetic anhydride at 120℃; for 3h; | 64% |
With potassium acetate In acetic anhydride at 120℃; for 1.5h; | 43% |
With potassium acetate; acetic anhydride at 120℃; for 2h; | 38% |
5-bromo-2-((2-nitroethenyl)amino)benzoic acid
6-bromo-3-nitroquinolin-4-ol
Conditions | Yield |
---|---|
With sodium acetate; acetic anhydride at 120℃; for 2h; | 60% |
With potassium acetate; acetic anhydride at 120℃; for 2h; | 60% |
With potassium acetate; acetic anhydride at 60 - 110℃; for 4h; | 56% |
6-bromo-3-nitroquinolin-4-ol
Conditions | Yield |
---|---|
With sodium acetate; acetic anhydride |
5-bromo-2-((2-nitroethenyl)amino)benzoic acid
acetic anhydride
6-bromo-3-nitroquinolin-4-ol
Conditions | Yield |
---|---|
With potassium acetate at 120℃; for 1.5h; |
5-Bromo-2-aminobenzoic acid
6-bromo-3-nitroquinolin-4-ol
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: hydrogenchloride / water / 24 h / 20 °C 2: 24 h / 20 °C 3: acetic anhydride; sodium acetate / 2 h / 120 °C View Scheme | |
Multi-step reaction with 3 steps 1: hydrogenchloride / water / 24 h / 20 °C 2: 24 h / 20 °C 3: acetic anhydride; potassium acetate / 2 h / 120 °C View Scheme | |
Multi-step reaction with 3 steps 1: hydrogenchloride / water / 24 h / 20 °C 2: 24 h / 20 °C 3: potassium acetate; acetic anhydride / 2 h / 120 °C View Scheme |
2-amino-5-bromobenzoic acid hydrochloride
6-bromo-3-nitroquinolin-4-ol
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 24 h / 20 °C 2: acetic anhydride; sodium acetate / 2 h / 120 °C View Scheme | |
Multi-step reaction with 2 steps 1: 24 h / 20 °C 2: acetic anhydride; potassium acetate / 2 h / 120 °C View Scheme | |
Multi-step reaction with 2 steps 1: 24 h / 20 °C 2: potassium acetate; acetic anhydride / 2 h / 120 °C View Scheme | |
Multi-step reaction with 2 steps 1.1: sodium hydroxide / water / 2.17 h / 0 - 20 °C 1.2: 0 °C 1.3: 18 h / 20 °C 2.1: potassium acetate; acetic anhydride / 1.5 h / 120 °C View Scheme |
4-bromo-aniline
6-bromo-3-nitroquinolin-4-ol
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1.1: ethanol / 0.17 h / 90 °C 1.2: 0.5 h 2.1: diphenylether / 0.08 h / 220 °C 3.1: nitric acid / propionic acid / 2 h / 125 °C View Scheme | |
Multi-step reaction with 3 steps 1: ethanol / 6 h / 105 °C 2: diphenylether / 0.25 h / 200 °C / Microwave irradiation 3: nitric acid / propionic acid / 2 h / 125 °C View Scheme |
C13H12BrNO4
6-bromo-3-nitroquinolin-4-ol
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: diphenylether / 0.08 h / 220 °C 2: nitric acid / propionic acid / 2 h / 125 °C View Scheme |
anthranilic acid
6-bromo-3-nitroquinolin-4-ol
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: ammonium bromide; dihydrogen peroxide; acetic acid / 16 h / 10 - 20 °C 2: ethanol / 18 h / 20 °C 3: potassium acetate; acetic anhydride / 2 h / 120 °C View Scheme |
This chemical is called 6-Bromo-4-hydroxy-3-nitroquinoline, and it's also named as 6-bromo-3-nitro-quinolin-4-ol. With the molecular formula of C9H5BrN2O3, its molecular weight is 269.05. The CAS registry number of this chemical is 853908-50-6.
Other characteristics of the 6-Bromo-4-hydroxy-3-nitroquinoline can be summarised as followings: (1)ACD/LogP: 2.42; (2)# of Rule of 5 Violations: 0; (3)ACD/BCF (pH 5.5): 1; (4)ACD/BCF (pH 7.4): 1; (5)ACD/KOC (pH 5.5): 1.785; (6)ACD/KOC (pH 7.4): 1; (7)#H bond acceptors: 5; (8)#H bond donors: 1; (9)#Freely Rotating Bonds: 2; (10)Polar Surface Area: 78.94 Å2; (11)Index of Refraction: 1.749; (12)Molar Refractivity: 58.304 cm3; (13)Molar Volume: 143.229 cm3; (14)Polarizability: 23.113×10-24cm3; (15)Surface Tension: 78.436 dyne/cm; (16)Density: 1.878 g/cm3; (17)Flash Point: 189.266 °C; (18)Enthalpy of Vaporization: 66.363 kJ/mol; (19)Boiling Point: 389.339 °C at 760 mmHg Vapour Pressure: 0 mmHg at 25°C.
You can still convert the following datas into molecular structure:
1.SMILES: c1cc2c(cc1Br)c(c(cn2)N(=O)=O)O
2.InChI: InChI=1/C9H5BrN2O3/c10-5-1-2-7-6(3-5)9(13)8(4-11-7)12(14)15/h1-4H,(H,11,13)
3.InChIKey: AMKJVYOALDEARM-UHFFFAOYAW