The 6-Chloroisatin is an organic compound with the formula C₈H₄ClNO₂. The systematic name of this chemical is 6-chloro-1H-indole-2,3-dione. With the CAS registry number 6341-92-0, it is also named as 1H-Indole-2,3-dione, 6-chloro-. The product's categories are Indane / Indanone and Derivatives; Indoles; Simple Indoles. In addition, the molecular weight is 181.58.

The other characteristics of this product can be summarized as: (1)ACD/LogP: 1.59; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 1.59; (4)ACD/LogD (pH 7.4): 1.57; (5)ACD/BCF (pH 5.5): 9.49; (6)ACD/BCF (pH 7.4): 9.16; (7)ACD/KOC (pH 5.5): 174.28; (8)ACD/KOC (pH 7.4): 168.16; (9)#H bond acceptors: 3; (10)#H bond donors: 1; (11)#Freely Rotating Bonds: 0; (12)Polar Surface Area: 37.38 Å²; (13)Index of Refraction: 1.626; (14)Molar Refractivity: 42.31 cm³; (15)Molar Volume: 119.5 cm³; (16)Polarizability: 16.77×10^-24 cm³; (17)Surface Tension: 56.8 dyne/cm; (18)Density: 1.519 g/cm³.

Preparation of 6-Chloroisatin: It can be obtained by 3,3-dibromo-6-chloro-1,3-dihydro-indol-2-one. This reaction needs reagent H₂O and solvent methanol by heating. The reaction time is 50 hours. The yield is 57%.

Uses of 6-Chloroisatin: It can react with (2-methoxy-phenyl)-acetic acid to get 7-chloro-3-(2-methoxyphenyl)-2-oxo-1,2-dihydroquinoline-4-carboxylic acid. This reaction needs reagent sodium acetate at temperature of 200-230 °C. The reaction time is 50min. The yield is 54%.

People can use the following data to convert to the molecule structure. 
1. SMILES:Clc1ccc2c(c1)NC(=O)C2=O
2. InChI:InChI=1/C8H4ClNO2/c9-4-1-2-5-6(3-4)10-8(12)7(5)11/h1-3H,(H,10,11,12)
3. InChIKey:RVXLBLSGEPQBIO-UHFFFAOYAL