Welcome to LookChem.com Sign In|Join Free
  • or
Home > Products >  > 

BRUCINE
Related Products

Hot Products

Basic Information Post buying leads Suppliers Cas Database
Name

BRUCINE

 EINECS 206-614-7
CAS No. 357-57-3 Density 1.41 g/cm3
PSA 51.24000 LogP 2.11260
Solubility slight Melting Point 175-178 ºC (dec.)
Formula C23H26 N2 O4 Boiling Point 633.7 °C at 760 mmHg
Molecular Weight 394.47 Flash Point 337.1 °C
Transport Information UN 1570 Appearance white crystalline powder
Safety A poison by subcutaneous, intravenous, and intraperitoneal routes. An alkaloid-like strychnine, but one-sixth as toxic. When heated to decomposition it emits toxic fumes of NOx. See also STRYCHNINE. Risk Codes R26/28;R52/53   
Molecular Structure Molecular Structure of 357-57-3 (10,11-Dimethoxystrychnine) Hazard Symbols
Synonyms

Brucine(8CI);4,6-Methano-6H,14H-indolo[3,2,1-ij]oxepino[2,3,4-de]pyrrolo[2,3-h]quinoline,strychnidin-10-one deriv.;(-)-Brucine;2,3-Dimethoxystrychnine;l-Brucine;

Article Data 12

BRUCINE Chemical Properties

Molecular Structure of BRUCINE(357-57-3):

Name:BRUCINE
Molecular Formula:C23H26N2O4
Molecular Weight:394.463540 g/mol
Melting Point:175-178 °C (dec.)(lit.)
Density:1.41 g/cm3
Flash Point:337.1 °C
Enthalpy of Vaporization:93.68 kJ/mol
Boiling Point:633.7 °C at 760 mmHg
Vapour Pressure:5.76E-16 mmHg at 25 °C
Water Solubility:482.3 mg/L at 25 °C
Alpha:-118 °(c=2.5 in chloroform)
EINECS:206-614-7
Synonyms of BRUCINE(357-57-3):
STRYCHNIDIN-10-ONE,2,3-DIMETHOXY;10,11-Dimethystrychnine;2,3-dimethoxy-strychnidin-10-on;2,3-Dimethoxystrychnidine-10-one;2,3-dimethoxy-strychnin;2,3-Dimethoxy-strychnine;Brucin;Brucina
Categories of BRUCINE(357-57-3):
Alkaloids;Organics;chiral;Miscellaneous Reagents;Biochemistry;for Resolution of Acids;Indole Alkaloids;Optical Resolution;Synthetic Organic Chemistry

BRUCINE Uses

BRUCINE(357-57-3) is primarily used in the regulation of high blood pressure and other comparatively benign cardiac ailments.

BRUCINE Toxicity Data With Reference

1.   

ipr-rat LD50:91 mg/kg

   JPETAB    Journal of Pharmacology and Experimental Therapeutics. 131 (1961),185.
2.   

scu-mus LD50:60 mg/kg

   APSXAS    Acta Pharmaceutica Suecdca. 7 (1970),329.
3.   

ivn-dog LDLo:8 mg/kg

   HBAMAK    “Abdernalden’s Handbuch der Biologischen Arbeitsmethoden.“ 4 (1935),1289.
4.   

ivn-rbt LDLo:30 mg/kg

   NTIS**    National Technical Information Service. (Springfield, VA 22161) (Formerly U.S. Clearinghouse for Scientific and Technical Information) PB214-270 .
5.   

ivn-gpg LDLo:120 mg/kg

   NTIS**    National Technical Information Service. (Springfield, VA 22161) (Formerly U.S. Clearinghouse for Scientific and Technical Information) PB214-270 .
6.   

scu-pgn LDLo:58 mg/kg

   HBAMAK    “Abdernalden’s Handbuch der Biologischen Arbeitsmethoden.“ 4 (1935),1289.

BRUCINE Consensus Reports

Reported in EPA TSCA Inventory.

BRUCINE Safety Profile

The safety information of BRUCINE(357-57-3) is as follows:
Hazard Codes:T+
Risk Statements:26/28-52/53
26/28:Very Toxic by inhalation and if swallowed
52/53:Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment
Safety Statements:13-45-61
13:Keep away from food, drink and animal feeding stuffs
45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
61:Avoid release to the environment. Refer to special instructions safety data sheet
RIDADR:UN 1570 6.1/PG 1
WGK Germany:3
RTECS:EH8925000
HazardClass:6.1(a)
PackingGroup:I
A poison by subcutaneous, intravenous, and intraperitoneal routes. An alkaloid-like strychnine, but one-sixth as toxic. When heated to decomposition it emits toxic fumes of NOx. See also STRYCHNINE.

BRUCINE Standards and Recommendations

DOT Classification:  6.1; Label: Poison
Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 357-57-3