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Benzeneethanamine,4-ethoxy-3-methoxy-

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Name

Benzeneethanamine,4-ethoxy-3-methoxy-

EINECS N/A
CAS No. 36377-59-0 Density 1.025 g/cm3
PSA 44.48000 LogP 2.29540
Solubility N/A Melting Point N/A
Formula C11H17NO2 Boiling Point 295.3 °C at 760 mmHg
Molecular Weight 195.261 Flash Point 144.1 °C
Transport Information N/A Appearance N/A
Safety 26-36/37/39 Risk Codes 36/37/38
Molecular Structure Molecular Structure of 36377-59-0 (4-ETHOXY-3-METHOXYPHENETHYLAMINE) Hazard Symbols IrritantXi
Synonyms

Phenethylamine,4-ethoxy-3-methoxy- (6CI);2-(4-Ethoxy-3-methoxyphenyl)ethanamine;3-Methoxy-4-ethoxyphenethylamine;4-Ethoxy-3-methoxyphenethylamine;

Article Data 20

Benzeneethanamine,4-ethoxy-3-methoxy- Synthetic route

54110-88-2

4-ethoxy-3-methoxy-β-nitro-styrene

36377-59-0

2-(4-ethoxy-3-methoxyphenyl)ethylamine

Conditions
ConditionsYield
at 65℃; bei der elektrolytischen Reduktion;
With hydrogenchloride; ethanol at 65℃; Electrolysis.bei der elektrolytischen Reduktion an Bleikathoden;
With lithium aluminium tetrahydride; diethyl ether; benzene
103796-52-7

4-ethoxy-3-methoxybenzylcyanide

36377-59-0

2-(4-ethoxy-3-methoxyphenyl)ethylamine

Conditions
ConditionsYield
With ammonia; nickel at 120 - 140℃; under 91938.4 Torr; Hydrogenation;
With sodium hydroxide; nickel Hydrogenation;
858783-47-8

3-(4-ethoxy-3-methoxy-phenyl)-propionic acid amide

36377-59-0

2-(4-ethoxy-3-methoxyphenyl)ethylamine

Conditions
ConditionsYield
With potassium hypobromite
With sodium hypochlorite
121670-34-6

3-(4-ethoxy-3-methoxy-phenyl)-propionic acid hydrazide

36377-59-0

2-(4-ethoxy-3-methoxyphenyl)ethylamine

Conditions
ConditionsYield
With hydrogenchloride; diethyl ether; sodium nitrite Erwaermen des Reaktionsprodukts mit Aethanol und anschliessend mit wss.NaOH;
54110-88-2

4-ethoxy-3-methoxy-β-nitro-styrene

64-19-7

acetic acid

hydrogen

hydrogen

platinum

platinum

36377-59-0

2-(4-ethoxy-3-methoxyphenyl)ethylamine

Conditions
ConditionsYield
nachfolgend Reduktion mit Natriumamalgam in Essigsaeure;
64-17-5

ethanol

54110-88-2

4-ethoxy-3-methoxy-β-nitro-styrene

64-19-7

acetic acid

zinc dust

zinc dust

36377-59-0

2-(4-ethoxy-3-methoxyphenyl)ethylamine

Conditions
ConditionsYield
nachfolgend Reduktion mit Natriumamalgam;
3-methoxy-4-ethoxy-DL-mandelonitrile

3-methoxy-4-ethoxy-DL-mandelonitrile

A

36377-59-0

2-(4-ethoxy-3-methoxyphenyl)ethylamine

B

1-(4-ethoxy-3-methoxy-phenyl)-2-amino-ethanol

Conditions
ConditionsYield
With palladium; acetic acid Hydrogenation;
53979-18-3

1-ethoxy-4-chloromethyl-2-methoxy-benzene

36377-59-0

2-(4-ethoxy-3-methoxyphenyl)ethylamine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: benzene
2: Raney nickel; ethanolic NH3 / 120 - 140 °C / 91938.4 Torr / Hydrogenation
View Scheme
30044-91-8

3-(4-ethoxy-3-methoxyphenyl)-propionic acid

36377-59-0

2-(4-ethoxy-3-methoxyphenyl)ethylamine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: thionyl chloride; chloroform / Eintragen des Reaktionsgemisches in ein Gemisch von wss. Natronlauge und wss. Ammoniak
2: aqueous sodium hypochlorite
View Scheme

C11H15NO4

36377-59-0

2-(4-ethoxy-3-methoxyphenyl)ethylamine

Conditions
ConditionsYield
With hydrogenchloride; zinc In ethanol; water for 3h;

Benzeneethanamine,4-ethoxy-3-methoxy- Specification

The Benzeneethanamine,4-ethoxy-3-methoxy- is an organic compound with the formula C11H17NO2. The IUPAC name of this chemical is 2-(4-ethoxy-3-methoxyphenyl)ethanamine. With the CAS registry number 36377-59-0, it is also named as 4-Ethoxy-3-methoxyphenethylamine.

Physical properties about Benzeneethanamine,4-ethoxy-3-methoxy- are: (1)ACD/LogP: 1.73; (2)ACD/LogD (pH 5.5): -1.34; (3)ACD/LogD (pH 7.4): -0.56; (4)ACD/BCF (pH 5.5): 1; (5)ACD/BCF (pH 7.4): 1; (6)ACD/KOC (pH 5.5): 1; (7)ACD/KOC (pH 7.4): 1.08; (8)#H bond acceptors: 3; (9)#H bond donors: 2; (10)#Freely Rotating Bonds: 6; (11)Polar Surface Area: 21.7 Å2; (12)Index of Refraction: 1.513; (13)Molar Refractivity: 57.32 cm3; (14)Molar Volume: 190.4 cm3; (15)Polarizability: 22.72×10-24cm3; (16)Surface Tension: 35.8 dyne/cm; (17)Density: 1.025 g/cm3; (18)Flash Point: 144.1 °C; (19)Enthalpy of Vaporization: 53.49 kJ/mol; (20)Boiling Point: 295.3 °C at 760 mmHg; (21)Vapour Pressure: 0.00154 mmHg at 25°C.

Uses of Benzeneethanamine,4-ethoxy-3-methoxy-: it can be used to produce 4-ethoxy-N-[2-(4-ethoxy-3-methoxy-phenyl)-ethyl]-5-methoxy-2-nitro-benzamide at ambient temperature. It will need solvent benzene. The yield is about 21%.

When you are using this chemical, please be cautious about it as the following:
This chemical is irritating to eyes, respiratory system and skin. When you are using it, wear suitable gloves and eye/face protection. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

You can still convert the following datas into molecular structure:
(1)SMILES: O(c1ccc(cc1OC)CCN)CC
(2)InChI: InChI=1/C11H17NO2/c1-3-14-10-5-4-9(6-7-12)8-11(10)13-2/h4-5,8H,3,6-7,12H2,1-2H3
(3)InChIKey: AFMUTJRFLRYILG-UHFFFAOYAD
(4)Std. InChI: InChI=1S/C11H17NO2/c1-3-14-10-5-4-9(6-7-12)8-11(10)13-2/h4-5,8H,3,6-7,12H2,1-2H3
(5)Std. InChIKey: AFMUTJRFLRYILG-UHFFFAOYSA-N

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