A Two Hour Synthesis of the Anti-Parkinson Drug Safinamide Methanesulfonate
The critical moment of the COVID-19 outbreak requires a real-time supply of therapeutic agents. Thus, time economy in the synthesis of biologically active compounds has become increasingly decisive. In this work, we developed a two hour synthesis of the a
Higa, Vanessa M.,Omori, Alvaro T.
p. 1433 - 1436
(2021/07/20)
Safinamide mesylate preparation method
The present invention belongs to the field of pharmaceutical synthesis, and provides a new safinamide mesylate preparation method. According to the present invention, m-fluorobenzyl chloride and p-hydroxybenzaldehyde are adopted as starting raw materials,
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Paragraph 0016
(2017/05/03)
Method for preparing industrial safinamide mesylate
The invention relates to a method for preparing industrial safinamide mesylate, and belongs to the technical field of organic synthesis. The method comprises the steps that a compound 3-fluorobenzylchloride and a compound p-hydroxy benzaldehyde react to g
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(2017/06/15)
PROCESS FOR THE PRODUCTION OF 2-[4-(3- OR 2-FLUOROBENZYLOXY)BENZYLAMINO]PROPANAMIDES WITH HIGH PURITY DEGREE
A process for obtaining therapeutically active 2-[4-(3- and 2-(flurobenzyloxy)benzylamino]propanamides, and their salts with pharmaceutically acceptable acids with high purity degree, in particular, with a content of dibenzyl derivatives impurities lower
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Page/Page column 72-73
(2009/07/17)
PROCESS FOR THE PRODUCTION OF 2- [4 - ( 3- AND 2-FLU0R0BENZYL0XY) BENZYLAMIN0] PROPAN AMIDES
A process for obtaining therapeutically active 2-[4-(3- and 2- (fluorobenzyloxy)benzylamino]propanamides and their salts with pharmaceutically acceptable acids with high purity degree, in particular, with a content of dibenzyl derivatives impurities lower
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(2008/06/13)
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