Exploration of carboxy pyrazole derivatives: Synthesis, alkaline phosphatase, nucleotide pyrophosphatase/phosphodiesterase and nucleoside triphosphate diphosphohydrolase inhibition studies with potential anticancer profile
In the present work we report the synthesis of new aryl pyrazole derivatives using 1,3-dicarbonyl motifs. The reaction was proceeded by the cyclization of pentane-2,4-dione (1a), 3-chloropentane-2,4-dione (1b) or ethyl 3-oxobutanoate (1c) with different a
Electronic effects on the structures and catalytic properties of (pyrazol-1-yl)phenylmethanone palladium(II) complexes
Four new (pyrazol-1-yl)phenylmethanone ligands and their palladium(II) complexes were synthesized and characterized by various analytical techniques. The electronic properties of substituents on the phenyl ring of the ligand have significant effects on th
Nelana, Simphiwe M.,Kumar, Kamlesh,Guzei, Ilia A.,Mahamo, Tebello,Darkwa, James
Iodonium salts as efficient iodine(iii)-based noncovalent organocatalysts for Knorr-type reactions
Hypervalent iodine(iii)-derivatives display higher catalytic activity than other aliphatic and aromatic iodine(i)- or bromine(i)-containing substrates for a Knorr-type reaction of N-acetyl hydrazides with acetyl acetone to give N-acyl pyrazoles. The highe
Yunusova, Sevilya N.,Novikov, Alexander S.,Soldatova, Natalia S.,Vovk, Mikhail A.,Bolotin, Dmitrii S.