Structure-Activity Relationships in an Imidazole-Based Series of Thromboxane Synthase Inhibitors
Analogues of 4-methyl>ethoxy>methyl>benzoic acid (5m) were prepared and evaluated as thromboxane synthase inhibitors.A series of esters of 5m showed a parabolic relationship between lipophilicity and inh
Manley, Paul W.,Allanson, Nigel M.,Booth, Robert F. G.,Buckle, Philip E.,Kuzniar, Edward J.,et al.
p. 1588 - 1595
(2007/10/02)
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