A versatile approach to β-amyloid fibril-binding compounds exploiting the shirakawa/hayashi protocol for trans-alkene synthesis
Application of the Sonogashira coupling reaction followed by a trans-selective alkyne reduction proved highly adaptable for the efficient synthesis of a class of β-amyloid fibril binding compounds possessing a styrylbenzene motif such as FSB, an FSB dimer
Huynh, Tri H. V.,Mantel, Mette Louise H.,Mikkelsen, Katrine,Lindhardt, Anders T.,Nielsen, Niels ChR.,Otzen, Daniel,Skrydstrup, Troels
supporting information; experimental part
p. 999 - 1002
(2009/07/18)
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