1116485-53-0

Basic information

• Product Name: methyl 5-((4-chloro-2-fluorophenyl)ethynyl)-2-(methylsulfonyloxy)benzoate
• Synonyms: methyl 5-((4-chloro-2-fluorophenyl)ethynyl)-2-(methylsulfonyloxy)benzoate
• CAS NO: 1116485-53-0
• Molecular Weight: 382.797
• Mol File: 1116485-53-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: methyl 5-((4-chloro-2-fluorophenyl)ethynyl)-2-(methylsulfonyloxy)benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 5-((4-chloro-2-fluorophenyl)ethynyl)-2-(methylsulfonyloxy)benzoate(1116485-53-0)
• EPA Substance Registry System: methyl 5-((4-chloro-2-fluorophenyl)ethynyl)-2-(methylsulfonyloxy)benzoate(1116485-53-0)

Safety Data

• Hazardous Substances Data: 1116485-53-0(Hazardous Substances Data)

Upstream product

• 1116485-51-8 methyl 5-ethynyl-2-(methylsulfonyloxy)benzoate 
• 6797-79-1 4-chloro-2-fluoro-1-iodobenzene 

Downstream Products

• 1116485-57-4 methyl 5-((4-((2,2-dimethyl-4-oxo-benzo[1,3]dioxin-6-yl)ethynyl)-2-fluorophenyl)ethynyl)-2-(methylsulfonyloxy)benzoate 

Relevant articles and documents

A versatile approach to β-amyloid fibril-binding compounds exploiting the shirakawa/hayashi protocol for trans-alkene synthesis

Application of the Sonogashira coupling reaction followed by a trans-selective alkyne reduction proved highly adaptable for the efficient synthesis of a class of β-amyloid fibril binding compounds possessing a styrylbenzene motif such as FSB, an FSB dimer