Synthesis and antifungal activity of a series of difluorotritylimidazoles
1-[(2-Fluorophenyl)(4-fluorophenyl)phenylmethyl]-1H-imidazole (flutrimazole, UR-4056, CAS 119006-77-8) (15) was selected among a series of mono-, di- and trifluorotrityl-imidazole antifungal agents as the most potent fluorine containing analogue of clotrimazole.
Bartroli,Alguero,Boncompte,Forn
p. 832 - 835
(2007/10/02)
1-((2-fluorophenyl)(4-fluorophenyl)phenylmethyl)-1H-imidazole useful as antifungal agent
The invention relates to 1-[(2-Fluorophenyl)(4-fluorophenyl)phenylmethyl]-1H-imidazole, useful as antifungal agent.