- Olprinone hydrochloride compound preparation method
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The invention discloses an olprinone hydrochloride compound preparation method. 6-bromoimidazo[1,2-a]pyridine is used as a starting material to prepare an olprinone hydrochloride compound through Grignard reaction, ozone oxidation, additive reaction, closed-loop reaction, salification and refining. The preparation process is mild in reaction condition, technically stable, high in repeatability andproduct yield, less in impurity and suitable for industrial production.
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Paragraph 0035; 0048-0050; 0051; 0060-0062; 0063; 0072-0074
(2019/04/17)
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