Highly enantioselective enzymatic resolution of aromatic β-amino acid amides with Pd-catalyzed racemization
The kinetic resolution of an aromatic β-amino acid amide 3a-d via N-acylation was explored with two lipases, Candida antarctica lipase A (CALA) and Pseudomonas stutzeri lipase (PSL). The PSL-catalyzed resolution proceeded with excellent enantioselectivity
Kim, Mahn-Joo,Choi, Eunjeong,Kim, Yunwoong,Ahn, Yangsoo,Park, Jaiwook
p. 1449 - 1452
(2013/12/04)
Enantioselective biocatalytic hydrolysis of β-aminonitriles to β-amino-amides using Rhodococcus rhodochrous ATCC BAA-870
A range of β-aminonitriles (3-amino-3-phenylpropanenitrile and derivatives) were synthesised by reaction of various benzonitriles with acetonitrile and subsequent reduction of the resulting acrylonitrile products. These compounds were hydrolysed to the co
Chhiba, Varsha,Bode, Moira L.,Mathiba, Kgama,Kwezi, Wendy,Brady, Dean
p. 68 - 74
(2012/04/10)
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