- NOVEL COMPOUNDS FOR DIAGNOSIS
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The present invention relates to novel compounds that can be employed in the diagnosis, monitoring of disease progression or monitoring of drug activity of a group of disorders and abnormalities associated with alpha-synuclein (α-synuclein, A-synuclein, aSynuclein, a- synuclein, A-syn, α-syn, aSyn, SNCA, Non-amyloid beta component of Alzheimer's disease (AD) amyloid plaques, Non-A4 component of amyloid precursor, NACP) aggregates including, but not limited to, Lewy bodies and/or Lewy neurites, such as Parkinson's disease (PD). The instant compounds are particularly useful in the diagnosis of the preclinical state of such a disorder, monitoring residual disorder, or predicting the responsiveness of a patient who is suffering from such a disorder to the treatment with a certain medicament.
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Page/Page column 50
(2019/12/28)
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- FUSED BICYCLIC COMPOUNDS AS INHIBITORS FOR PI3 KINASE
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The invention relates to compounds of formula (I) for the regulation of phosphoinositides 3-kinases activity and related diseases.
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Page/Page column 109
(2010/09/18)
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- Formation and Pyrolysis of 1-(2'-Thiazolopyridyl)-5-aryltetrazoles
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1-(2'-Thiazolopyridyl)-5-aryltetrazoles (4) have been obtained by the reaction of 2-aroylaminothiazolopyridines (2) with phosphorus pentachloride and azidolysis of the resulting imidoyl chlorides.The products of pyrolysis of 1-(2'-thiazolopyridyl)-5-aryltetrazoles in decalin have been characterised as 2-aryl-1,2,4-triazolothiazolopyridines (6).
- Prasad, V.S.R.,Sambaiah, T.,Reddy, K. Kondal
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p. 1983 - 1988
(2007/10/02)
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