- Synthesis, characterization and photodynamic activity against bladder cancer cells of novel triazole-porphyrin derivatives
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Novel triazole-porphyrin derivatives (TZ-PORs) were synthesized through the Heck reaction and then incorporated into polyvinylpyrrolidone (PVP) micelles. After verifying that this incorporation did not compromise the photophysical and chemical features of
- Gomes, Ana T.P.C.,Fernandes, Rosa,Ribeiro, Carlos F.,Tomé, Jo?o P.C.,Neves, Maria G.P.M.S.,da Silva, Fernando de C.,Ferreira, Vítor F.,Cavaleiro, José A.S.
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- Synthesis and evaluation of the cytotoxic activity of Furanaphthoquinones tethered to 1H-1,2,3-triazoles in Caco-2, Calu-3, MDA-MB231 cells
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Naphthoquinones and 1,2,3-triazoles are structural pharmacophore that is known to impart several cancer cells. This work shows a synthetic methodology to obtain hybrid molecules involving naphthoquinone and triazol scaffold as multiple ligands. A simple a
- Costa, Dora C.S.,de Almeida, Gabriella Silva,Rabelo, Vitor Won-Held,Cabral, Lucio Mendes,Sathler, Plínio Cunha,Alvarez Abreu, Paula,Ferreira, Vitor Francisco,Cláudio Rodrigues Pereira da Silva, Luiz,da Silva, Fernando de C.
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p. 524 - 533
(2018/07/25)
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- Synthesis of 1H-1,2,3-triazoles and study of their antifungal and cytotoxicity activities
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We report herein the results of antifungal activity of fifteen 1,2,3-triazoles against Candida albicans, Candida krusei, Candida parapsilosis, Candida kefyr, Candida tropicalis, Candida dubliniensis, Tricophyton rubrum, Microporum canis and Aspergillus ni
- Da Silva, Iara F.,Martins, Prisicila R.C.,Da Silva, Emanuelly G.,Ferreira, Sabrina B.,Ferreira, Vitor F.,Da Costa, Karen Regina C.,De Vasconcellos, Marne C.,Lima, Emerson S.,Da Silva, Fernando De C.
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p. 1085 - 1090
(2014/01/06)
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- Novel 1,2,3-triazole derivatives for use against mycobacterium tuberculosis H37Rv (ATCC 27294) strain
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The purpose of this study was to prepare various 4-substituted N-phenyl-1,2,3-triazole derivatives using click chemistry. The derivatives were screened in vitro for antimicrobial activity against Mycobacterium tuberculosis strain H37Rv (ATCC 27294) using
- Boechat, Nubia,Ferreira, Vitor F.,Ferreira, Sabrina B.,Ferreira, Maria De Lourdes G.,Da Silva, Fernando De C.,Bastos, Monica M.,Costa, Marilia Dos S.,Louren?o, Maria Cristina S.,Pinto, Angelo C.,Krettli, Antoniana U.,Aguiar, Anna Caroline,Teixeira, Brunno M.,Da Silva, Nathalia V.,Martins, Priscila R. C.,Bezerra, Flavio Augusto F. M.,Camilo, Ane Louise S.,Da Silva, Gerson P.,Costa, Carolina C. P.
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p. 5988 - 5999
(2011/10/09)
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