Synthesis of bis-indole carboxamides as G-quadruplex stabilizing and inducing ligands
The design and synthesis of a series of bis-indole carboxamides with varying amine containing side chains as G-quadruplex DNA stabilising small molecules are reported. Their interactions with quadruplexes have been evaluated by means of Foerster resonance
Dash, Jyotirmayee,Nath Das, Rabindra,Hegde, Nagaratna,Pantoa, G. Dan,Shirude, Pravin S.,Balasubramanian, Shankar