4-Oxo-1,4-dihydropyridines as selective CB2 cannabinoid receptor ligands part 2: Discovery of new agonists endowed with protective effect against experimental colitis
Further on to our earlier work on the 4-oxo-1,4-dihydropyridine, we describe herein our strategy to get access to potent selective CB2 receptor agonists. Thus, we designed and synthesized 29 compounds, evaluated on both hCB1 and hCB