1403498-92-9Relevant articles and documents
4-Oxo-1,4-dihydropyridines as selective CB2 cannabinoid receptor ligands part 2: Discovery of new agonists endowed with protective effect against experimental colitis
El Bakali, Jamal,Gilleron, Pauline,Mansouri, Roxane,Barczyk, Amelie,Klupsch, Frederique,Andrzejak, Virginie,Chavatte, Philippe,Millet, Regis,Body-Malapel, Mathilde,Djouina, Madjid,Desreumaux, Pierre,Muccioli, Giulio G.,Lambert, Didier M.,Lipka, Emmanuelle,Furman, Christophe
, p. 8948 - 8952,5 (2020/09/16)
Further on to our earlier work on the 4-oxo-1,4-dihydropyridine, we describe herein our strategy to get access to potent selective CB2 receptor agonists. Thus, we designed and synthesized 29 compounds, evaluated on both hCB1 and hCB