- The fluorine atom as a cation-stabilizing auxiliary in biomimetic polyene cyclizations: Total synthesis of dl-dammarenediol
-
Dammarenediols I (1a) and II (1b) were prepared by an efficient nonenzymatic biomimetic polyene tetracyclization route. The cyclization substrate, pentaenol 3, contains a tetramethylallylic alcohol initiator, an allyltrimethylsilane terminating group, and
- Johnson, William S.,Bartlett, William R.,Czeskis, Boris A.,Gautier, Arnaud,Lee, Cheol H.,Lemoine, Remy,Leopold, Eric J.,Luedtke, Gregory R.,Bancroft, Katherine J.
-
-
Read Online
- Synthesis and properties of 2-cyanoethoxy derivatives of dammarane triterpenoids
-
Cyanoethylation of dammaran-3β-ols and 3-oxime dammarene, semisynthetic derivatives of the natural dipterocarpol, afforded a series of new dammarane triterpenoids containing 2-cyanoethoxy fragment at the carbon atom in the position 3 of the tetracyclic scaffold. A notable antiviral activity was found in 20(S)-3-[(2-cyanoethoxy)imino]-dammar-24-en-20-ol and 20(S)-3-O-(2-cyanoethyl)-25,26,27-trinor-20,24-olidedammarane.
- Kaledina,Zorina,Zarubaev,Anokhina,Erkhitueva,Trifonov
-
-
Read Online
- Synthesis and Cytotoxicity of Derivatives of Dipterocarpol, a Metabolite of Dipterocarpus alatus
-
New derivatives with hydroxy, epoxy, hydroxyimino, acetoxy, lactol, methoxylactol, and indole groups in ring A and the side chain were synthesized via chemical transformations of dipterocarpol. The structure- cytotoxicity relationship was described for the dipterocarpol derivatives.
- Huong, Do Thi Thu,Thuy, Tran Thi Thu,Hien, Tran Thi,Tra, Nguyen Thanh,Tien, Nguyen Quyet,Smirnova,Kazakova,Minnibaeva,Tolstikov
-
-
Read Online
- Ozonolysis of dipterocarpol and its derivatives
-
Oxidation of dipterocarpol and its derivatives with ozone gave compounds containing lactone, lactol, alkoxytetrahydrofuran, aldehyde, and methyl ketone fragments in the side chain, as well as 1,2,4-trioxolane fragment in the A ring. The molecular and crystalline structures of dipterocarpol were determined by X-ray analysis. Pleiades Publishing, Ltd., 2012.
- Smirnova,Thu, H. Do Thi,Kazakova,Tolstikov,Kukovinets,Lobov,Suponitskii
-
p. 1370 - 1376
(2013/02/22)
-
- Polymeric derivatives of dipterocarpol, a dammarane triterpenoid
-
Polymeric derivatives of dammarane triterpenoids with both labile and strong (covalent) polymer-triterpenoid bonds were prepared from N-vinylpyrrolidone copolymers. Pleiades Publishing, Inc., 2006.
- Zorina,Balykina,Nazarova,Rebezov
-
p. 654 - 659
(2008/02/09)
-
- In vitro conversion of 2,3-oxidosqualene into dammarenediol by Panax ginseng microsomes
-
(RS)-[3-3H]-2,3-Oxidosqualene (1) was converted into (20S)- dammarenediol (2) and not to (20R)-dammarenediol by a microsomal fraction prepared from the hairy root of Panax ginseng. The enzyme activity was highest at pH 6.0 and was not increased by the addition of any detergents. These properties differed significantly from those of other 2,3-oxidosqualene cyclases reported from higher plants and animals.
- Kushiro, Tetsuo,Ohno, Yoshimi,Shibuya, Masaaki,Ebizuka, Yutaka
-
p. 292 - 294
(2007/10/03)
-