The invention relates to compounds of formula (I): and their pharmaceutically acceptable salts and solvates, which are inhibitors of SSAO activity. The invention further relates to pharmaceutical compositions comprising these compounds and to the use of these compounds for the treatment or prevention of medical conditions wherein inhibition of SSAO activity is beneficial, such as inflammatory diseases and immune disorders.
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Page/Page column 79-80
(2010/06/20)
Synthesis of 2-arylimidazo[1,2-a]pyrimidines by the Chichibabin synthesis in ionic liquids
A series of 2-arylimidazo[1,2-a]pyrimidines has been synthesised in excellent yields by the Chichibabin synthesis in room temperature ionic liquids.
Xu, Danqian,Liu, Baoyou,Zheng, Mei
p. 645 - 647
(2007/10/03)
Synthesis and antibacterial activity of some imidazo[1,2-a[pyrimidine derivatives
A series of 75 imidazo[1,2-a]pyrimidine derivatives were synthesized. The 'in vitro' antibacterial activity of these compounds and their corresponding α-bromoketones against a variety of gram (+), gram (-) bacteria and Mycobacterium species is reported. Some of the prepared derivatives exhibited potent antimicrobial activity.
Rival,Grassy,Michel
p. 1170 - 1176
(2007/10/02)
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