143696-74-6

Basic information

• Product Name: 2-(2,4-DICHLOROPHENYL)IMIDAZO[1,2-A]PYRIMIDINE
• Synonyms: 2-(2,4-DICHLOROPHENYL)IMIDAZO[1,2-A]PYRIMIDINE
• CAS NO: 143696-74-6
• Molecular Formula: C₁₂H₇Cl₂N₃
• Molecular Weight: 264.11008
• Mol File: 143696-74-6.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-(2,4-DICHLOROPHENYL)IMIDAZO[1,2-A]PYRIMIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2,4-DICHLOROPHENYL)IMIDAZO[1,2-A]PYRIMIDINE(143696-74-6)
• EPA Substance Registry System: 2-(2,4-DICHLOROPHENYL)IMIDAZO[1,2-A]PYRIMIDINE(143696-74-6)

Safety Data

• Hazardous Substances Data: 143696-74-6(Hazardous Substances Data)

Upstream product

• 109-12-6 2-aminopyrimidine 
• 4252-78-2 2,2',4'-trichloroacetophenone 
• 2234-16-4 1-(2,4-dichlorophenyl)ethan-1-one 
• 2631-72-3 2,4-dichlorophenacyl bromide 

Downstream Products

• 1228303-88-5 [2-(2,4-dichlorophenyl)imidazo[1,2-a]pyrimidin-3-yl]methanol 
• 143696-93-9 2-(2,4-Dichloro-phenyl)-3-nitro-imidazo[1,2-a]pyrimidine 
• 143696-87-1 3-nitroso-2-(2,4-dichlorophenyl)imidazo(1,2-a)pyrimidine 

Relevant articles and documents

IMIDAZOPYRIDINE COMPOUNDS

The invention relates to compounds of formula (I): and their pharmaceutically acceptable salts and solvates, which are inhibitors of SSAO activity. The invention further relates to pharmaceutical compositions comprising these compounds and to the use of these compounds for the treatment or prevention of medical conditions wherein inhibition of SSAO activity is beneficial, such as inflammatory diseases and immune disorders.

Synthesis and antibacterial activity of some imidazo[1,2-a[pyrimidine derivatives

A series of 75 imidazo[1,2-a]pyrimidine derivatives were synthesized. The 'in vitro' antibacterial activity of these compounds and their corresponding α-bromoketones against a variety of gram (+), gram (-) bacteria and Mycobacterium species is reported. Some of the prepared derivatives exhibited potent antimicrobial activity.