- HETEROCYCLIC AMIDES AS KINASE INHIBITORS
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Disclosed are compounds having the formula: wherein R1 and R2 are as defined herein, and methods of making and using the same.
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Page/Page column 165; 166
(2018/06/06)
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- Pyrimidine, quinazoline, pteridine and triazine derivatives
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This invention is concerned with compounds of the formula wherein A, R1 to R5 and G are as defined in the description and claims, and pharmaceutically acceptable salts thereof. The invention further relates to pharmaceutical compositions containing such compounds, to a process for their preparation and to their use for the treatment and/or prevention of diseases which are associated with the modulation of SST receptors subtype 5.
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Page/Page column 33
(2008/06/13)
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- Products of a microbiological process for the production of 2-halo-pyrimidine-4-carboxylic acids
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A 2-halo-pyrimidine-4-carboxylic acid of formula: STR1 wherein X is a halogen atom, for example, 2-chloro-pyrimidine-4-carboxylic acid. A 2-substituted-pyrimidine-4-carboxylic acid derivative of formula: STR2 wherein R1 is a halogen atom, NH2 --, HO-- or a C1 -C4 alkoxy group and R2 is a C1 -C4 alkoxy group or a halogen atom with the proviso that, if R1 is a HO-- group, R2 is not a halogen atom and with the proviso that, if R2 is a halo group, R1 is not an amino group. A 2-substituted-pyrimidine-4-carboxylic acid derivative of formula III wherein R1 is a HO-- group and R2 is an ethoxy group.
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