Synthesis of Benzo-Fused Benzodiazepines Employed as Probes of the Agonist Pharmacophore of Benzodiazepine Receptors
The synthesis and in vitro evaluation of benzo-fused benzodiazepines 1-6 are described.These "molecular yardsticks" were employed to probe the spatial dimensions of the lipophilic pocket L2 in the benzodiazepine receptor (BzR) cleft and to dete
Zhang, Weijiang,Koehler, Konrad F.,Harris, Bradford,Skolnick, Phil,Cook, James M.
p. 745 - 757
(2007/10/02)
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