cas 16034-49-4, (3,5-DIMETHYL-PYRAZOL-1-YL)-ACETIC ACID | Articles data ｜lookchem

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16034-49-4

Articles about 16034-49-4Total 5 be found

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Simple method for the synthesis of 3,5-dimethylpyrazolyl-1-acetic acid
-
Nam,Grandberg,Sorokin
p. 382 - 382
(1998)
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CHEMICAL SUBSTANCES WHICH INHIBIT THE ENZYMATIC ACTIVITY OF HUMAN KALLIKREIN-RELATED PEPTIDASE 6 (KLK6)
The invention relates to compounds which are suitable for the treatment of a disease associated with kallikrein-like peptidase 6 overexpression and to pharmaceutical compositions containing such compounds. The invention further relates to a kit of parts comprising such compounds or pharmaceutical compositions.
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Paragraph 0363; 0364

(2018/04/19)

COMPOUNDS USEFUL AS CSF1 MODULATORS
This invention relates to novel compounds and to pharmaceutical compositions comprising the novel compounds. More specifically, the invention relates to compounds useful as Colony Stimulating Factor 1 Receptor (cFMS) modulators (e.g. cFMS inhibitors). This invention also relates to processes for preparing the compounds, uses of the compounds in treatment and methods of treatment employing the compounds. Specifically, the invention relates to the use of the compounds for the treatment of cancer and autoimmune diseases.
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Paragraph 00573; 00576; 00577

(2016/04/26)

Alkylation of pyrazoles with ethyl chloroacetate under phase-transfer catalysis and hydrolysis of the esters obtained
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Rstakyan,Hakobyan,Zakaryan,Hayotsyan,Attaryan,Asratyan
p. 1641 - 1643
(2015/02/19)

Aqueous hydrolysis of pyrazol-1-ylacetates
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Badalyan,Asratyan,Attaryan
experimental part
p. 946 - 946
(2012/09/25)

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Chemical Properties

Melting Point: 186-192°C
Boiling Point: 306.759 °C at 760 mmHg
Flash Point:139.323 °C
Density: 1.234 g/cm³
Storage Temp.:2-8°C
Vapor Pressure: 0.000329mmHg at 25°C
PKA: 2.57±0.10(Predicted)
PSA: 55.12000
LogP: 0.58450

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