16034-49-4

Basic information

• Product Name: (3,5-DIMETHYL-PYRAZOL-1-YL)-ACETIC ACID
• Synonyms: TIMTEC-BB SBB006999;ART-CHEM-BB B003362;IFLAB-BB F0452-6137;CHEMBRDG-BB 4400183;(3,5-DIMETHYL-1H-PYRAZOL-1-YL)ACETIC ACID;(3,5-DIMETHYL-PYRAZOL-1-YL)-ACETIC ACID;AKOS BBS-00005857;AKOS AU36-M95
• CAS NO: 16034-49-4
• Molecular Formula: C7H10N2O2
• Molecular Weight: 154.17
• Mol File: 16034-49-4.mol
• Article Data: 5

Chemical Properties

• Melting Point: 186-192°C
• Boiling Point: 306.759 °C at 760 mmHg
• Flash Point: 139.323 °C
• Appearance: /
• Density: 1.234 g/cm³
• Vapor Pressure: 0.000329mmHg at 25°C
• Storage Temp.: 2-8°C
• PKA: 2.57±0.10(Predicted)
• CAS DataBase Reference: (3,5-DIMETHYL-PYRAZOL-1-YL)-ACETIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: (3,5-DIMETHYL-PYRAZOL-1-YL)-ACETIC ACID(16034-49-4)
• EPA Substance Registry System: (3,5-DIMETHYL-PYRAZOL-1-YL)-ACETIC ACID(16034-49-4)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 22
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 16034-49-4(Hazardous Substances Data)

Usage

General Description

(3,5-DIMETHYL-PYRAZOL-1-YL)-ACETIC ACID is a chemical compound with the molecular formula C7H10N2O2. It is a derivative of pyrazole with a methyl group attached at the 3 and 5 positions and an acetic acid group attached at the pyrazole nitrogen. (3,5-DIMETHYL-PYRAZOL-1-YL)-ACETIC ACID is often used in organic synthesis and pharmaceutical research as a building block or intermediate for the synthesis of various functionalized pyrazole derivatives. It may also have potential applications in drug discovery and development due to its unique structural properties and potential biological activity. Additionally, (3,5-DIMETHYL-PYRAZOL-1-YL)-ACETIC ACID is used in laboratory settings as a reagent or catalyst for various chemical reactions.

InChI:InChI=1/C7H10N2O2/c1-5-3-6(2)9(8-5)4-7(10)11/h3H,4H2,1-2H3,(H,10,11)/p-1

Upstream product

• 79559-08-3 methyl 2-(3,5-dimethyl-1H-pyrazol-1-yl)acetate 
• 1449369-11-2 benzyl 2-(3,5-dimethyl-1H-pyrazol-1-yl)acetate 
• 67-51-6 3,5-dimethyl-1H-pyrazole 
• 10199-60-7 ethyl 2-(3,5-dimethyl-1H-pyrazol-1-yl)acetate 
• 79-11-8 chloroacetic acid 

Downstream Products

• 1253382-59-0 N-(2-amino-phenyl)-2-{4-[2-(3,5-dimethyl-pyrazol-1-yl)-acetyl]-piperazin-1-yl}-benzamide 
• 1253936-85-4 1-{4-[2-(1H-benzoimidazol-2-yl)phenyl]piperazin-1-yl}-2-(3,5-dimethyl-pyrazol-1-yl)ethanone 
• 1253936-87-6 2-(3,5-dimethyl-pyrazol-1-yl)-1-{4-[2-(5-trifluoromethyl-1H-benzoimidazol-2-yl)phenyl]piperazin-1-yl}ethanone 
• 1253383-72-0 N-(5-chloro-2-{4-[2-(3,5-dimethyl-pyrazol-1-yl)-acetyl]-piperazin-1-yl}-pyridin-3-yl)-4-methanesulfonyl-benzamide 
• 1253383-61-7 3-chloro-N-(5-chloro-2-{4-[2-(3,5-dimethyl-pyrazol-1-yl)-acetyl]-piperazin-1-yl}-pyridin-3-yl)-benzamide 
• 1253382-55-6 2-{4-[2-(3,5-dimethyl-pyrazol-1-yl)-acetyl]-piperazin-1-yl}-N-pyridin-4-yl-benzamide 
• 1253383-29-7 N-(2-{4-[2-(3,5-dimethyl-pyrazol-1-yl)-acetyl]-piperazin-1-yl}-phenyl)-benzamide 
• 1253383-31-1 1-[4-(2-amino-phenyl)-piperazin-1-yl]-2-(3,5-dimethyl-pyrazol-1-yl)-ethanone 
• 1253382-57-8 2-{4-[2-(3,5-dimethyl-pyrazol-1-yl)-acetyl]-piperazin-1-yl}-benzoic acid 
• 1449369-11-2 benzyl 2-(3,5-dimethyl-1H-pyrazol-1-yl)acetate 
• 1253383-75-3 3-chloro-N-(5-chloro-2-{4-[2-(3,5-dimethyl-pyrazol-1-yl)-acetyl]-[1,4]diazepan-1-yl}-pyridin-3-yl)-benzamide 
• 1253383-65-1 1-[4-(5-chloro-3-nitro-pyridin-2-yl)-piperazin-1-yl]-2-(3,5-dimethyl-pyrazol-1-yl)-ethanone 
• 1253381-44-0 2-{4-[2-(3,5-dimethyl-pyrazol-1-yl)-acetyl]-piperazin-1-yl}-N-phenyl-benzamide 
• 1253383-30-0 2-(3,5-dimethyl-pyrazol-1-yl)-1-[4-(2-nitro-phenyl)-piperazin-1-yl]-ethanone 

Relevant articles and documents

Simple method for the synthesis of 3,5-dimethylpyrazolyl-1-acetic acid

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COMPOUNDS USEFUL AS CSF1 MODULATORS

This invention relates to novel compounds and to pharmaceutical compositions comprising the novel compounds. More specifically, the invention relates to compounds useful as Colony Stimulating Factor 1 Receptor (cFMS) modulators (e.g. cFMS inhibitors). This invention also relates to processes for preparing the compounds, uses of the compounds in treatment and methods of treatment employing the compounds. Specifically, the invention relates to the use of the compounds for the treatment of cancer and autoimmune diseases.

Aqueous hydrolysis of pyrazol-1-ylacetates

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