Metal catalyst-free by design. the synthesis of amides from alkyl iodides, carbon monoxide and amines by a hybrid radical/ionic reaction
Amides can be synthesized from alkyl iodides and amines in the presence of CO (20-25 atm), without using transition metal catalyst; the radical cascade is initiated thermally using AIBN and allyltributyltin.
A general and practical method of synthesis of 2-disubstituted-1- chloro- and 1-bromoenamines
Disubstituted-α-chloroenamines are useful synthetic intermediates which had earlier been prepared by the reaction of tertiary amides with phosgene. The toxicity of the latter led us to systematically investigate new synthetic routes towards α-chloro- and