18940-58-4 Usage
Description
1,4-Diisobutyrylpiperazine is an organic compound that is primarily utilized as a reactant in the synthetic preparation of chloro enamines and bromo enamines. It is a derivative of piperazine, a heterocyclic amine, and features two isobutyryl groups attached to the piperazine ring. 1,4-Diisobutyrylpiperazine has been investigated for its potential analgesic properties, which could make it a valuable asset in the pharmaceutical industry.
Uses
Used in Pharmaceutical Industry:
1,4-Diisobutyrylpiperazine is used as a reactant for the synthetic preparation of chloro enamines and bromo enamines, which are important intermediates in the synthesis of various pharmaceutical compounds. These enamines are key building blocks for the development of new drugs with potential applications in treating a wide range of medical conditions.
1,4-Diisobutyrylpiperazine is also used as a potential analgesic agent for the development of pain-relieving medications. Its investigation in this area highlights the compound's potential to contribute to the creation of new and effective pain management solutions.
Check Digit Verification of cas no
The CAS Registry Mumber 18940-58-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,8,9,4 and 0 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 18940-58:
(7*1)+(6*8)+(5*9)+(4*4)+(3*0)+(2*5)+(1*8)=134
134 % 10 = 4
So 18940-58-4 is a valid CAS Registry Number.
InChI:InChI=1/C12H22N2O2/c1-9(2)11(15)13-5-7-14(8-6-13)12(16)10(3)4/h9-10H,5-8H2,1-4H3
18940-58-4Relevant articles and documents
Metal catalyst-free by design. the synthesis of amides from alkyl iodides, carbon monoxide and amines by a hybrid radical/ionic reaction
Ryu, Ilhyong,Nagahara, Kiyoto,Kambe, Nobuaki,Sonoda, Noboru,Kreimerman, Sergio,Komatsu, Mitsuo
, p. 1953 - 1954 (1998)
Amides can be synthesized from alkyl iodides and amines in the presence of CO (20-25 atm), without using transition metal catalyst; the radical cascade is initiated thermally using AIBN and allyltributyltin.
New analgetic agents. V. 1-butyryl-4-cinnamylpiperazine hydrochloride and related compounds.
Irikura,Masuzawa,Nishino,Kitagawa,Uchida,Ichinoseki,Ito
, p. 801 - 804 (2007/10/04)
-