- Method for triggering hydroxy selective acylation of dihydric alcohol or polyhydric alcohol by catalytic amount of organic amine
-
The invention belongs to the field of organic chemical engineering, and particularly provides a method for triggering hydroxy selective acylation of dihydric alcohol or polyhydric alcohol by a catalytic amount of organic amine. According to the method, dihydric alcohol or polyhydric alcohol dissolves in an appropriate amount of organic solvents, a chemical amount of anhydride and the catalytic amount of organic amine are added, N,N-diisopropylethylamine is added particularly, reaction is conducted at the temperature of 0-50 DEG C for 4-12 hours, and high-selectivity acylation on specific hydroxyl can be realized. The method has the advantages that reaction conditions are mild, the method is simple and convenient to operate, inhibitors are green, environmentally friendly, low in cost and easy to get, and the method has wide application value in labs and industries.
- -
-
Paragraph 0021
(2018/10/27)
-
- Catalytic Alkynylation of Cyclic Acetals and Ketals Enabled by Synergistic Gold(I)/Trimethylsilyl Catalysis
-
A completely regioselective and challenging gold(I)-catalyzed ring-opening of cyclic 1,3-dioxolanes and dioxanes by trimethylsilyl alkynes to set diol-derived propargyl trimethylsilyl bis-ethers is reported. This unprecedented and not trivial transformation does not operate with the catalytic methodologies recently reported for catalytic alkynylation of acyclic acetals/ketals, and is uniquely enabled by the application of a recently introduced synergistic gold(I)-silicon catalysis concept capable of producing simultaneously catalytic amounts of two key players, a silicon-based Lewis superacid and a nucleophilic gold acetylide.
- Berthet, Mathéo,Songis, Olivier,Taillier, Catherine,Dalla, Vincent
-
p. 9916 - 9922
(2017/09/23)
-
- A two-benzoic acid preparation method of dihydric alcohol ester plasticizers (by machine translation)
-
A two-benzoic acid dihydric alcohol ester plasticizers of the preparation method, the method to benzoic acid and dihydric alcohol as raw materials, in under the catalytic action, 100 - 250 °C, to carry out the esterification reaction, the reaction 0.5 - 48h. By distilling under reduced pressure, to obtain two-benzoic acid dihydric alcohol ester product. Two-benzoic acid ester is a non-toxic alcohol plasticizer, can replace the phthalic acid ester used for plastic, rubber in the industry field. The method for preparing the product of high yield, product is easy to separate, environment friendly, has very good application prospect. (by machine translation)
- -
-
Paragraph 0018
(2017/06/14)
-
- Personal care products containing high refractive index esters and methods of preparing the same
-
The invention includes personal care compositions and methods of preparing these personal care compositions that include incorporation of a polyol polyester that is the reaction product of an aliphatic polyol that does not contain an ether group, and benzoic acid, wherein the resultant polyol polyester has a refractive index at 25° C. of greater than about 1.5. The aliphatic polyol may have two to three carbon atoms. Alternatively, the invention includes personal care compositions and methods of preparing personal care compositions including incorporating a polyol polyester into a personal care formulation. The polyol polyester is represented by formula (I): wherein R is an aliphatic alkyl group that does not contain an ether group and has a refractive index of greater than about 1.5 at 25° C. Also described are methods of preparing personal care compositions comprising a first phase and a second phase, wherein the second phase contains any of the polyol polyesters described above.
- -
-
Page/Page column 4
(2008/06/13)
-
- PERSONAL CARE PRODUCTS CONTAINING HIGH REFRACTIVE INDEX ESTERS AND METHODS OF PREPARING THE SAME
-
The invention includes personal care compositions and methods of preparing these personal care compositions that include incorporation of a polyol polyester that is the reaction product of an aliphatic polyol that does not contain an ether group, and benzoic acid, wherein the resultant polyol polyester has a refractive index at 25° C of greater than about 1.5. The aliphatic polyol may have two to three carbon atoms. Alternatively, the invention includes personal care compositions and methods of preparing personal care compositions including incorporating a polyol polyester into a personal care formulation. The polyol polyester is represented by formula (I): wherein R is an aliphatic alkyl group that does not contain an ether group and has a refractive index of greater than about 1.5 at 25° C. Also described are methods of preparing personal care compositions comprising a first phase and a second phase, wherein the second phase contains any of the polyol polyesters described above.
- -
-
Page/Page column 9
(2008/06/13)
-
- 'Green' methodology for efficient and selective benzoylation of nucleosides using benzoyl cyanide in an ionic liquid
-
Benzoyl cyanide in the ionic liquid 1-methoxyethyl-3-methylimidazolium methanesulfonate has been employed as a 'green' alternative and mild reaction condition protocol to conventional pyridine-benzoyl chloride system for efficient and selective benzoylation of nucleosides (of both the ribo- and deoxyribo-series) at ambient temperatures. The use of benzoyl cyanide-ionic liquid combination has been successfully extended for highly efficient benzoylation of phenols, aromatic amines, benzyl alcohol, aliphatic diols, 3-aminophenol and 2-aminobenzylalcohol, which indicates the versatility of this benzoylating system.
- Prasad, Ashok K.,Kumar, Vineet,Malhotra, Shashwat,Ravikumar, Vasulinga T.,Sanghvi, Yogesh S.,Parmar, Virinder S.
-
p. 4467 - 4472
(2007/10/03)
-
- Solubilizing agents for active or functional organic compounds
-
An active or functional organic compound is solubilized in a diaryl organic compound having a polar or polarizable functional group therein, as a solvent, cosolvent or additive, to form a composition thereof. Representative active or functional organic compounds include those present in personal care products, e.g., sunscreens containing UVA/UVB absorbing compounds, such as avobenzone, benzophenone-3, and 4-methylbenzylidene camphor. Such compositions also show increased SPF, UVA/UVB absorbance ratio, and critical wavelength performance properties.
- -
-
-
- Antiperspirant compositions
-
Antiperspirant compositions comprise an antiperspirant active and a carrier oil in which the carrier oil comprises an aromatic ester oil obeying the general formula: [in-line-formulae]R1—CO2—X—Y—R2 [/in-line-formulae] in which R1 and R2 each represent a phenyl group, X represents an alkylene group containing from 2 to 4 carbons including at least one pendant alkyl group and Y represents a bond, or an ether or ester linkage.
- -
-
Page/Page column 8
(2008/06/13)
-
- Organotin-Mediated Monoacylation of Diols with Reversed Chemoselectivity: A Convenient Synthetic Method
-
The organotin-mediated monoesterification of unsymmetrical diols with reversed chemoselectivity has been explored to ascertain scope and limits of the method and to provide an easy and convenient synthetic procedure.The reaction has been performed on a set of substituted diols with some acylating agents usually employed as protecting groups.Two different procedures have been devised to obtain either the desired diol monoesters directly or the corresponding trialkylsilyl ethers as protected derivatives.The latter provides a convenient approach to the preparation of easily interconvertible diol monoesters.Also, the reaction has been optimized as a one-pot procedure, avoiding the isolation and purification of the stannylated intermediates.The reversed monoesterification method has been successfully applied to 1,2-, 1,3-, and 1,4-diols of primary-secondary, primary-tertiary, and secondary-tertiary types and to ether functions containing 1,2-diols.Within its limits, the described method represents the first direct one-pot monoesterification of diols at the most substituted site, allowing some remarkable achievements as (a) an almost regiospecific reversed monobenzoylation of some 1,2-diols, (b) the selective acylation of the tertiary hydroxyl of a primary-tertiary diol, and (c) a highly selective preparation of secondary pivalate of primary-secondary diols.
- Reginato, Gianna,Ricci, Alfredo,Roelens, Stefano,Scapecchi, Serena
-
p. 5132 - 5139
(2007/10/02)
-
- Chemoselective Benzoylations of 1,2-Diols. Reactivity Comparisons of Reagents. Triphenylphosphine-Benzoyl Peroxide and Triphenylphosphine-Diethyl Azodicarboxylate-Benzoic Acid
-
The triphenylphosphine-benzoyl peroxide (TPP-BPO) reagent initiates stereospecific benzoylation of secondary carbinol stereocenters with essentially complete inversion of stereochemistry.Monobenzoylations of 1,2-propanediol and styrene glycol with TPP-BPO and triphenylphosphine-diethyl azodicarboxylate-benzoic acid reagents afford a predominance of the more sterically encumbered C-2 benzoate with complete inversion of stereochemistry.Formation of a quintessential 1,3,2λ5-dioxaphospholane intermediate, followed by proton-assisted and highly stereoselective ring opening of the phospholanes to isomeric oxyphosphonium ions, allows for Arbusov displacement of triphenylphosphine oxide by benzoate anion.This rationale adequately accounts for both the high chemoselectivity and the stereochemistry of the reactions.
- Pautard, Anne M.,Evans, Slayton A.
-
p. 2300 - 2303
(2007/10/02)
-
- Disperse dye composition for use in solvent dyeing
-
A disperse dye concentrate for use in non-aqueous solvent systems, employing a disperse dye, comprises 10-95% by weight of dry disperse dye, free of water-soluble dispersing agents, admixed with one or more of: (A) a cycloaliphatic diester of the formula STR1 wherein R is straight or branched chain alkyl of 4-20 carbon atoms, polyoxyalkylene of the formula HO(CH2 CH2 O)n CH2 CH2 --, HO(C3 H6 O)n C3 H6 --, HO(CH2 CH2)p (C3 H6 O)q C3 H6 -- or HO(C3 H6 O)p (CH2 CH2 O)q CH2 CH2 -- or phosphated polyoxyalkylene, wherein n is 2-22 and the sum of p+q is n; (B) a high boiling aromatic ester of the formula wherein R1 is alkylene of 2-8 carbon atoms or polyoxyalkylene of the formula --Cr H2r (OCr H2r)s --, in which r is 2 or 3 and s is 1 to 15; R2 is substituted or unsubstituted alkyl or alkenyl of 8-30 carbon atoms and Ar is substituted or unsubstituted mono- or bicyclic aryl of up to 15 carbon atoms; or (C) a high boiling alkylphenol ester of an aliphatic or aromatic monocarboxylic acid or a phosphoric acid of the formula wherein R4 is the residue of an ethoxylated alkylphenol of the formula STR2 wherein a is 0-12 and b is 1-24 or an ethoxylated alkanol residue of the formula wherein c is 7-22, d is 1-24 and R3 is linear or branched chain alkyl of 1-21 carbon atoms, phenyl or tolyl.
- -
-
-
- DIALKYL ACYLPHOSPHONATES: A NEW ACYLATING AGENT OF ALCOHOLS
-
Diethyl benzoylphosphonate (1) underwent facile benzoylation of alcohols in the presence of DBU.Reactions of diols containing primary and secondary hydroxyl groups with 1 gave predominantly monobenzoates in which primary hydroxyl groups were highly selectively benzoylated.Related acylations were also described.
- Sekine, Mitsuo,Kume, Akiko,Hata, Tsujiaki
-
p. 3617 - 3620
(2007/10/02)
-