cas 199336-05-5, TRANS (1S,2S)-1N-CBZ-CYCLOHEXANE-1,2-DIAMINE

Articles about 199336-05-5Total 4 be found

Solvent-induced reversal of enantioselectivity in the synthesis of succinimides by the addition of aldehydes to maleimides catalysed by carbamate-monoprotected 1,2-diamines
A simple change in the polarity of the solvent allows both enantiomers of substituted succinimides to be obtained in the enantioselective conjugate addition reaction of aldehydes, mainly disubstituted, to maleimides catalysed by chiral carbamate-monoprote
Flores-Ferrndiz, Jess,Fiser, Bla,Gmez-Bengoa, Enrique,Chinchilla, Rafael
p. 1218 - 1225
(2015/03/04)

Design, synthesis, and biological evaluation of pirenzepine analogs bearing a 1,2-cyclohexanediamine and perhydroquinoxaline units in exchange for the piperazine ring as antimuscarinics
Pirenzepine (2) is one of the most selective muscarinic M1 versus M2 receptor antagonists known. A series of 2 analogs, in which the piperazyl moiety was replaced by a cis- and trans-cyclohexane-1,2-diamine (3-6) or a trans- and cis-
Minarini, Anna,Marucci, Gabriella,Bellucci, Cristina,Giorgi, Gianluca,Tumiatti, Vincenzo,Bolognesi, Maria Laura,Matera, Riccardo,Rosini, Michela,Melchiorre, Carlo
p. 7311 - 7320
(2008/12/22)

A novel bifunctional sulfonamide primary amine-catalyzed enantioselective conjugate addition of ketones to nitroolefins
The enantioselective conjugate addition of a variety of ketones to nitroolefins has been developed. The process is efficiently catalyzed by a novel bifunctional sulfonamide primary amine in good yields and with good levels of enantioselectivity.
Xue, Fei,Zhang, Shilei,Duan, Wenhu,Wang, Wei
supporting information; experimental part
p. 2194 - 2198
(2009/10/02)

Stereochemical influence on the stability of radio-metal complexes in vivo. Synthesis and evaluation of the four stereoisomers of 2-(p- nitrobenzyl)-trans-CyDTPA
Distinct differences in in vivo stability of the two diastereomeric C- Functionalized CyDTPA chelating agents, (CHX-A DTPA and CHX-B DTPA, both racemates), as recently reported prompted further investigation as to why differences in configuration produced striking effects on the in vivo stability of their yttrium complexes. To this end, the four individual component stereoisomers of CHX-A and CHX-B were synthesized and ability to bind yttrium was investigated both in vitro and in vivo.
Wu,Kobayashi,Sun,Yoo,Paik,Gansow,Carrasquillo,Pastan,Brechbiel
p. 1925 - 1934
(2007/10/03)