- Intermediate compound, and synthetic method of prothioconazole
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The invention discloses an intermediate compound, and a synthetic method of prothioconazole. The method comprises the following steps: carrying out a substation reaction on 5,5'-dithio-bis(1,2,4-triazole) and 2-(1-chlorocyclopropyl)-3-chloro-1-(2-chlorophenyl)-2-propanol to obtain the key intermediate compound; and reducing the key intermediate compound to obtain the target product prothioconazole. The synthetic method has the advantages of high conversion rate, high selectivity, cheap and easily available synthesis raw materials, reduction of the production cost, mild and easily controlled technologic reaction conditions, simplicity in operation, easiness in product purification, obtaining of the product through direct re-crystallization, simple and accurate control method of intermediates in all steps, high product yield, good atom economy, avoiding of tedious post-treatment, large competition advantages and industrial production utilization values, avoiding of strong alkalis and other raw materials, extremely low three wastes, and according with the green chemistry idea.
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- Triazolyl disulphides
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PCT No. PCT/EP97/02282 Sec. 371 Date Nov. 5, 1998 Sec. 102(e) Date Nov. 5, 1998 PCT Filed May 5, 1997 PCT Pub. No. WO97/43269 PCT Pub. Date Nov. 20, 1997The present invention provides the composition for novel triazolyl disulphides, the acid addition salts and metal salt complexes of the triazolyl disulphides, a process for their preparation, and a method for their use as microbicides.
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