- Selective N-Monoalkylation of Amide Derivatives with Trialkyl Phosphates
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A highly selective and easily handled monoalkylation of primary amide derivatives by using trialkyl phosphates as alkylating reagents in cyclopentyl methyl ether (CPME) was developed. Various monoalkylated amide derivatives were efficiently synthesized by changing the alkyl moiety (e.g., methyl, ethyl, butyl, or benzyl) of the trialkyl phosphate. These phosphate reagents are relatively stable and easily available, and CPME is a useful solvent in process chemistry.
- Asai, Shota,Ban, Kazuho,Monguchi, Yasunari,Sajiki, Hironao,Sawama, Yoshinari
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supporting information
p. 322 - 325
(2017/10/31)
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- A METHOD OF TREATING PERIPHERAL INFLAMMATORY DISEASE
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An active for use in the treatment or inhibition of an inflammatory disease associated with over-activation of Toll-like Receptor 4 (TLR4), Toll-like Receptor 2 (TLR2) and Myeloid differentiating protein 88 (Myd88) adaptor-like protein (Mal) while maintaining a subject's ability to respond normally to a pathogen, in which the active is an oleamide or a derivative thereof.
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Paragraph 0078-0084; 0129-0130
(2016/12/01)
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- Compounds suitable for use in inks and inks having such compounds
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Disclosed herein are amide compounds suitable for use in ink compositions, and methods of making the amide compounds disclosed herein.
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Page/Page column 24
(2009/09/26)
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