MULTICYCLIC PEPTIDES AND METHODS FOR THEIR PREPARATION
The invention relates to methods for preparing a compound comprising a peptide attached to a molecular scaffold whereby multiple peptide loops are formed, to compounds that can be obtained with such methods and uses thereof.
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(2018/06/30)
MACROCYCLIC PEPTIDOMIMETICS FOR ALPHA-HELIX MIMICRY
Methods and compositions are provided for generating macrocyclic peptides constrained by side-chain-to-C-terminus non-peptidic tethers for use as functional and structural mimics of α-helical motifs, including in therapeutic applications. These methods can be used to produce libraries of conformationally constrained peptidomimetics to identify compounds with desired activity properties.
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Paragraph 00252
(2015/11/02)
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