- FLUOROISOQUINOLINE SUBSTITUTED THIAZOLE COMPOUNDS AND METHODS OF USE
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The invention relates to thiazole compounds of Formula (I) and compositions thereof useful for treating diseases mediated by protein kinase B (PKB) where the variables have the definitions provided herein. The invention also relates to the therapeutic use of such thiazole compounds and compositions thereof in treating disease states associated with abnormal cell growth, cancer, inflammation, and metabolic disorders.
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Page/Page column 69-70
(2010/08/08)
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- N-(5-MEMBERED AROMATIC RING)-AMIDO ANTI-VIRAL COMPOUNDS
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Disclosed are compounds having Formula (I) and the compositions and methods thereof for treating or preventing a viral infection mediated at least in part by a virus in the Flaviviridae family of viruses, wherein A, R2, m, R, V, W, T, Z, R
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Page/Page column 103
(2008/06/13)
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- Synthesis of a chiral bis(bipyridine) ligand of the Chiragen family for the self-assembly of enantiomerically pure helicates
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The chiral bis(bipyridine) ligand L, belonging to the 'chiragen' family, has been synthesized. The synthetic pathway involves an original preparation of acylnicotinates which is of synthetic value. The synthetic strategy described here may allow the acces
- Baret, Paul,Einhorn, Jacques,Gellon, Gisele,Pierre, Jean-Louis
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p. 431 - 435
(2007/10/03)
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