207672-16-0Relevant articles and documents
FLUOROISOQUINOLINE SUBSTITUTED THIAZOLE COMPOUNDS AND METHODS OF USE
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Page/Page column 69-70, (2010/08/08)
The invention relates to thiazole compounds of Formula (I) and compositions thereof useful for treating diseases mediated by protein kinase B (PKB) where the variables have the definitions provided herein. The invention also relates to the therapeutic use of such thiazole compounds and compositions thereof in treating disease states associated with abnormal cell growth, cancer, inflammation, and metabolic disorders.
Synthesis of a chiral bis(bipyridine) ligand of the Chiragen family for the self-assembly of enantiomerically pure helicates
Baret, Paul,Einhorn, Jacques,Gellon, Gisele,Pierre, Jean-Louis
, p. 431 - 435 (2007/10/03)
The chiral bis(bipyridine) ligand L, belonging to the 'chiragen' family, has been synthesized. The synthetic pathway involves an original preparation of acylnicotinates which is of synthetic value. The synthetic strategy described here may allow the acces