- A Novel Reagent for Labelling Macromolecules with Intensely Luminescent Lanthanide Complexes
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A novel bifunctional chelator, 4-iodoacetamidodipicolinic acid, has been synthesized in three steps starting with chelidamic acid, and used to prepare protein conjugates that form stable and intensely luminescent complexes with Tb(III) and Eu(III).The excited state lifetime of Tb(III) complexes with this reagent was 1.25 ms, permitting its use for ultrasensitive time-resolved luminescence assays.
- Lamture, Jagannath B.,Wensel, Theodore G.
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- Design and synthesis of complementary components for the formation of self-assembled supramolecular rigid rods
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The complementary components AP2 and AU2, resulting respectively from the linking of diacylaminopyridine and uracil derivatives to an anthracenic core, have been designed in order to self-assemble, through hydrogen bonding, into polymeric supramolecular rigid rods (AP2, AU2)(n). The synthesis of these compounds is reported.
- Kotera, Mitsu,Lehn, Jean-Marie,Vigneron, Jean-Pierre
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- Selective cytotoxicity and luminescence imaging of cancer cells with a dipicolinato-based EuIII complex
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Four new species [Ln(dipicNH2)3]3- (Ln = LaIII, EuIII, GdIII, TbIII), with the ligand dipicNH22- (dipic = dipicolinato), were synthesized. Incubation of the EuIII complex with glioma NG97 and pancreatic cancer PANC1 cells showed that it penetrates the cell membrane and can be used to image the cells, while also being moderately cytotoxic.
- Monteiro,Machado,De Hollanda,Lancellotti,Sigoli,De Bettencourt-Dias
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- Modified Colorants and Inkjet Ink Compositions Comprising Modified Colorants
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The present invention relates to a modified colorant comprising a colorant having attached at least one organic group. Various embodiments of the organic group are disclosed. For each of these embodiments, preferably the organic group has a defined calciu
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Paragraph 0148-0149
(2016/04/09)
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- Cation Complexing Properties of Synthetic Macrocyclic Polyether-Diester Ligands Containing the Pyridine Subcyclic Unit
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Ten new macrocyclic polyether-diester compounds containing a pyridine subcyclic unit substituted in the 4 position with chloro or methoxy groups have been prepared.These compounds along with their unsubstituted pyridine analogues form strong complexes wit
- Bradshaw, J. S.,Maas, G. E.,Lamb, J. D.,Izatt, R. M.,Christensen J. J.
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p. 467 - 474
(2007/10/02)
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