- Cascade cyclization of 1,2-diamino-4-phenylimidazole with aromatic aldehydes and cyclohexanediones
-
The three-component condensation of 1,2-diamino-4-phenylimidazole with aromatic aldehydes and 1,3-cyclohexanediones occurred regioselectively and afforded 3-amino-1-phenyl-10-aryl-7,8-dihydroimidazo[1,5-b] cinnolin-9(5H,6H, 10H)-ones. Pleiades Publishing, Ltd., 2012.
- Lipson,Svetlichnaya,Shirobokov,Musatov,Shishkin,Shishkina
-
supporting information; experimental part
p. 273 - 277
(2012/05/21)
-
- Synthesis of nitrogen-containing heterocycles 10 [1]. Reaction of 2-amino- 1H-imidazole derivatives with ethoxymethylene compounds
-
The direct annelation reaction of 4-substituted 2-amino-1-benzylideneamino-1H-imidazoles (1) or 2-amino-1-isopropylideneamino-1H-imidazole (8) with ethoxymethylenemalononitrile (I) gave successfully bicyclic imidazo[1,2-a]pyrimidine compounds 2 and 9 in high yields. The reactions of other ethoxymethylene compounds of lower reactivity, i.e., ethyl ethoxymethylenecyanoacetate (II) and diethyl ethoxymethylenemalonate (III), with 2-amino-1H-imidazoles under similar conditions afforded the corresponding enamines 3, 4 and 10, which, upon heating in the presence of an acid or a base, could readily be cyclized to form imidazopyrimidines except for 1-isopropylideneamino compound 10. In general, the 3-phenyl compounds (3b and 4b) did not cyclize to the type 2 compound resulting in a full recovery of the starting enamines.
- Miyamoto, Yoshiko
-
p. 157 - 162
(2007/10/03)
-
- Synthesis of dihydro derivatives of 2-amino-4,5,7-triarylimidazo[1,5-b]pyridazine
-
7-Amino-2,4,5-triaryl-3,4-dihydroimidazo[1,5-b]pyridazines have been synthesized by reacting 4-aryl-1,2-diaminoimidazoles with 1,3-diarylpropenones. The structure of one of the products was confirmed by X-ray structural analysis. 1999 Kluwer Academic/Plen
- Kolos,Orlov,Paponov,Shishkin
-
p. 1207 - 1213
(2007/10/03)
-
- Synthesis of substituted 2-amino-1-arylidenaminoimidazoles and 1-arylidenaminoimidazo[1,2-a]imidazoles
-
A new method is proposed for the preparation of 2-amino-1-arylidenaminoimidazoles, which react with α-haloketones to give a series of 1-arylidenamino-3-acylmethyl-2-iminoimidazolines and 1-arylidenaminoimidazo[1,2-a]imidazoles depending on the conditions. 1997 Plenum Publishing Corporation.
- Krimer,Makaev,Styngach,Koretskii,Pogrebnoi,Kochug
-
p. 1035 - 1039
(2007/10/03)
-