A new synthesis of 2-substituted pyridines via aluminum chloride induced heteroarylation of arenes and heteroarenes
(Chemical Equation Presented) We herein report a new synthesis of 2-(hetero)aryl-substituted pyridines via heteroarylation of arenes/heteroarenes through AlCl3-induced C-C bond-forming reactions. 2-Halopyridines bearing an electron-withdrawing group were reacted with a number of (hetero)arenes to give 2-aryl/heteroaryl-substituted pyridines in good yields.